A Meta-analysis Of Alcoholic Liver Disease TCM Medication

Purpose:Alcoholic liver disease, ALD is a pathological change caused by excessive intake of ethanol or alcohol which causes liver damage, which can develop from fatty degeneration to an advanced stage of the disease, such as, cirrhosis even liver cancer. According to statistics,60%of chronic alcoholics have fatty liver, and almost20%-30%patients will eventually develop into cirrhosis. The hazard of this disease has aroused great attention worldwide, especially the incidence of hepatocellular carcinoma. There are about70%fatal diseases have close relationship with the liver disease. Traditional Chinese medicine believes that the cause of this disease is liver stagnation and spleen deficiency, phlegm and dampness. Chinese medicine from the overall perspective, using syndrome differentiation theory in treatment of alcoholic liver disease has good curative effect in some cases or some aspects, not in every case, such as the improvement of liver function, reducing mortality rate, decreasing the occurrence of liver cirrhosis. With the improvement of people’s living conditions, alcoholic liver damage caused by excessive drinking is more common. So the research on preventing and treatment of alcoholic liver disease is more important. This article will overview from alcoholic liver disease in TCM disease name, etiology, pathogenesis, therapeutical principles, syndrome differentiation and treatment of traditional Chinese medicine, and make a brief analysis on alcoholic liver disease from multiple syndromes angle, combining with the summarization of the status of clinical diagnosis and treatment of alcoholic liver disease, the preferred solutions were briefly TCM diagnosis,prevention and treatment of traditional Chinese medicine, and the direction for the future treatment of ALD.Materials and methods:retrieval in medical journals, academic conferences and dissertations on alcoholic liver disease in TCM(Traditional Chinese Medicine) clinical research literature published from2008January to2013January. All cases conform to the formulation of the inclusion and exclusion criteria of this subject.Results: This study extracts a total of1133cases of literature,28prescriptions, including112kinds of Medicine (not repeat), used drug13050times. TCM (Traditional Chinese Medicine) syndrome classification ratio is mainly:Retention of damp-heat syndrome,44.13%; liver stagnation and spleen deficiency syndrome,33.89%; qi stagnation and blood stasis,10.94%, disharmony between liver and stomach syndrome,7.15%; damp-heat in liver and gallbladder,6.88%. The retention of damp-heat syndrome in the literature involves a total of466cases, including a total of101herbs which are used for4919times; liver stagnation and spleen deficiency literature involves a total of384Cases, including a total of133herbs, which are used for4488times; qistagnation and blood stasis literature involving a total of124cases, including a total of39herbs, which are used for1636times; damp-heat in liver and gallbladder the number of cases of literature in81cases, including a total of26drug, which are used for987times; disharmony between liver and stomach literature involving a total of78cases, including a total of26drug, which are used for1020times.Conclusion:Traditional Chinese medicine believes that this disease is caused by metabolism derivatives of excessive drinking alcohol, which is caused by the hot of food and drink, poly sputum, retention of damp-heat in. Clinically, patients should be cured based on the specific circumstances and therapeutic rules in Chinese Traditional Medicine and embody the theory of traditional Chinese medicine treatments that treat the different diseases with the same method and the same disease with different methods.The implementation of individualized treatment strategies can lead to better results.