Bone Health Gluten Soup With Fumigation Efficacy Study Of Knee Osteoarthritis Treatment

Purpose：To observe the impact of bone health capsule rabbit model of knee osteoarthritis of theknee joint synovial IL-1.Material and method：33rabbits were randomly divided into treatmentgroups of10，the modelgroup11and acontrolgroup of12. Administrationgroup，modelgroup line Hulth technique replicated themodel of osteoarthritis after5w600mg/kggavage administration ofgroup health Capsule，modelgroup and controlgroupgiven normal saline orally administered three weeks afteranatomical microscope downstream cartilage Pelletier，JP，score，take the medial femoralcondyle articular cartilage line Masson and toluidine blue staining observed collagen fibers incartilage proteoglycan content changes，immunohistochemical detection of cartilage andsynovium of IL-1expression situation.Results: bone health capsules can delay the loss of articular cartilage matrix inosteoarthritis， the cartilage and synovial IL-1expression of the treatmentgroup wassignificantly lower than the modelgroup (P <0.05).Results：Bone health capsules can delay the loss of articular cartilage matrix in osteoarthritis，thecartilage and synovial IL-1expression of the treatmentgroup was significantly lower than themodelgroup (P <0.05).