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Clinical Research Yiqihuoxue Prescription On Chronic Heart Failure Efficacy Evaluation

Posted on:2014-02-17Degree:MasterType:Thesis
Country:ChinaCandidate:H YangFull Text:PDF
GTID:2264330425474555Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Purpose:This topic aims to apply yiqi huoxue compound for the treatment ofchronic heart failure patients with qi deficiency blood stasis type water park,observation of the side of chronic heart failure the curative effect of patientswith qi deficiency blood stasis type water park and the influence of the long-termprognosis in patients with chronic heart failure, so as to establish standar-dization of chronic heart failure clinical treatment of traditional Chinesemedicine, the curative effect of yiqi huoxue compound for the treatment ofchronic heart failure is put forward evaluation system, provides an effectivenew drug of traditional Chinese medicines for the treatment of chronic heartfailure, for laying a foundation for application of Chinese medicine treatmentof chronic heart failure in the future.Material and method:hospitalforSeptember,2011totheout-patientserviceand hospitalized sufferer in May,2012, and match diagnosis standard and bringinto standard, add up to80.Press according to the random number form1:1therandom number producing is divided into a treatment set, matched control, each40for each.Adopt random the list Be blind to check against method to carry onprospect to random check against a clinical research to the qualifiedtest-receiver.The matched control gives the doctor norm the treatment, thetreatment set adds on the foundation of doctor norm treatment with the benefitspirit to live the blood compound prescribe(this square be square for experiencethat professor Zhang Yan cures heart Shuai, entrust this river medicine industryto make into a grain) each the bag10gs, a bag of each time, three times takeorally on the first.Take the medicine period as a month, observe after the front,under medical treatment and treatment of two sets of cases treatment heartfunction ratings, empress heart Shuai curative effect integral calculus, Chinesemedicine symptom and Chinese medicine the certificate wait integral calculusand live variety and normal regulations of quality integral calculus to monitorbad reaction index sign and stop to carry on to two sets of sufferers after threemonths, six months and nine months after the medicine telephone with visit withvisit. Results:1.Before curing, two sets of cases the age, the sex, course of illnessand heart function ratings and heart Shuai integral calculus, Chinese medicinecertificate’s waiting integral calculus and life quality integral calculus alldon’t show Zhao difference(P all>0.05) and explained2sets before treatmenthave can compare sex, random the cent set effect is opposite and good.2.Treatment set heart function improvement circumstance of always effici-ent:97.5%;The matched control heart function improves Class alwaysefficient:95.0%.Treatment set’s showing an efficiency is higher than a matchedcontrol and explain that the treatment set is equal with matched control curativeeffect in the aspects of improving heart function.3.Two groups of patients with heart failure after integral radit analysisrespectively, significant efficiency, efficient treatment group and controlgroup compared with significant difference (P <0.05); Two groups of inefficiency,the increase rate and total effective rate (*+effective) had no significantdifference (P>0.05).4.Two sets of Chinese medicine certificates wait before curing the integralcalculus didn’t show Zhao difference(P>0.05), two sets of difference inside setsin the front and back of the treatment showed Zhao(P<0.05), and the set differenceshows Zhao.(P<0.05)Hint2sets all can reduce a Chinese medicine certificateto wait integral calculus, treatment set better than matched control.5.After two sets of sufferers accept a treatment, each life quality grade pointobviously improvement, and the improvement effect of the treatment set obviouslysurpasses a matched control and explains that the benefit spirit lives bloodcompound prescribe to obviously raise the sufferer’s living quality.6.Cure two sets of sufferer’s6minuteses ago on foot distance relatively don’tshow Zhao difference(P>0.05), cured inside the front and back set, set all havealready shown Zhao difference.(P<0.05)Hint2sets all can increase on footdistance of6minutes, and treatment set better than matched control.7.The treatment set always stops to reduce to lead to62.5%, the matched controlalways stops to reduce to lead47.5%, and two sets of total curative effect arethrough the card square’s examination:X2=60.126, P=0.000;P<0.05, explain twosets of comparison the difference have a statistics to learn meaning(P<0.05)8.Treatment set always again hospitalization lead to12.5%, matched controlalways again hospitalization lead to22.5%,2set always again hospitalization lead through the card square’s examination:X2=9.931, P=0.019, P<0.05, thereis statistics learning meaning, explain a treatment set that leading in totalhospitalization for9months is lower than matched control.9.The treatment set total satisfaction is90.0%, the matched control totalsatisfaction is82.5%, and two sets of total satisfaction are through the cardsquare’s examination:X2=26.209, P=0.000, P<0.05, there is statistics learningmeaning, explain a treatment set the sufferer compares matched control suffererto treatment project of curative effect satisfaction Gao.10.Two sets of sufferers all have no obvious or severity of poisonous pairreaction, safety with bear to be subjected to sex all good.Conclusion:The benefit spirit lived the clinical symptom, heart functionand Chinese medicine the symptoms integral calculus, living quality and etc.that the blood compound prescribe improves a chronic heart Shuai(heart functionⅡ, Ⅲ class) debility blood Yu water stopped sufferer to obtain good curativeeffect.Pass to two sets of sufferers and stop for three months, six months andnine months after the medicine of then hospitalization rate of with visit,investigate a result to suggest, added to live blood Chinese herbal medicineto lower a sufferer with the benefit spirit of then hospitalization lead,probably has aggressive influence towards improving chronic heart Shuai overa long period of time preparing of the sufferer behind and cures the expansionapplication of heart Shuai to lay foundation for aftertime’s Chinese medicinemedicine.
Keywords/Search Tags:choronic heart failure, Yi qi huo xue fu fang, Clinicalresearch, therapeutic evaluation
PDF Full Text Request
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