Repeated Transurethral Resecttion Of Bladder Tumor For Non-Musscle Invasive Bladder Cancer

Objective Investigation and discussion of the first transurethral resection of bladder tumor (TURBT) and repeated transurethral resection of the bladder tumor (Re-TURBT) in the treatment of non-muscle invasive bladder cancer and comparison of two kinds of different operation methods in effects of postoperative recurrence rate, safety comparison operation and positive rate of (Re-TURBT) tumor resection associated risk factors.Methods Regression analysis of medical records and follow-up data in our hospital from2007July to2012December,169patients underwent conventional transurethral resection of bladder tumor (TURBT) and32cases of Re-TURBT. Comparison of two surgical methods in postoperative recurrence rate, operation time, postoperative hospital stay, indwelling catheter time to analyze the influencing factors and positive rate of (Re-TURBT) tumor resection associated risk factors.Results Two kinds of different operation methods in postoperative recurrence rate was statistically significant difference (X2=3.918, P<0.05) considers that two operation methods were different in postop recurrence rate, postop recurrence rate was significantly lower in Re-TURBT group than in conventional TURBT group and operation time (t=-0.195, P=0.846), hospitalization time (t=1.423, P=0.156), indwelling catheter time (t=-0.466, P=0.642) of two different surgical methods prompt that there was no statistically significant difference.According to the logistic binary regression analysis showed:the first (TURBT) tumor resection for≥T1(X2=4.891, P=0.04), high grade tumors (G2and G3)(X2=1.903, P=0.001), tumor size more than3cm (X2=9.718, P=0.004), multiple tumors (≥2)(X2=6.203, P=0.02) are independent risk factors of positive rate of (Re-TURBT) tumor resection."pathological grade of the first (TURBT) tumor resection " have a great contribution to the regression equation.Conclusion Repeated transurethral resection of bladder tumor (Re-TURBT) has the advantages of simple operation, safety in operation, short hospitalization time, reduce the postop recurrence rate, with regard to the first (TURBT) for multiple tumors, larger tumors (≥3cm), high grade tumors and high stage tumors (≥T1)etc. especially the first transurethral resection of bladder tumor (TURBT) for high grade tumor should be underwent conventional repeated transurethral resection of bladder tumor (Re-TURBT).