| Objective:To investigate the physical characteristics of TCM (traditional Chinese medicine)in patients with recurrent stroke.Methods:360cases of recurrent stroke were enrolled in our study.The investigation included the following aspects:(1) The distribution of nine constitutions in Traditional Chinese Medicine(TCM) including the constitution of Ordinary, Qi deficiency, Yang deficiency, Yin deficiency, Phlegm-dampness, damp-heat, blood stasis, Qi-stagnation and special intrinsic quality in patients with recurrent stroke.(2) To investigate the relationship of constitutions of TCM and sex, age, weight in360cases of recurrent stroke patients.(3) Found that there are differences between different physical integration of risk factors, including the patient gentleness below Yin deficiency and blood stasis from relapse risk factor analysis. Physical type analysis found that patients with recurrent stroke risk factors in each merging Phlegm-dampness, Yin deficiency and blood stasis more, but with no significant difference in the incidence of various types of physical risk factors in patients. In our study, Most patients with hypertension, diabetes, carotid artery plaque, more than half with diabetes and carotid plaques, more than one-third of the combined. So we concluded that high blood pressure, diabetes, and carotid artery plaque were major risk factors for recurrent stroke.(4) Physical type of relationship with NIHSS:nerve function defect in patients with Ordinary lighter than Qi deficiency, blood stasis, Yin deficiency patients, the difference was statistically significant (P<0.05). Physical type relationship with the Barthel Index score: quality of daily living in patients with Ordinary high blood stasis score, Yin deficiency and Qi deficiency patients, the difference was statistically significant (P<0.05). The relationship between physical type and MRS:Yin deficiency, blood stasis, Qi deficiency high quality of daily life dependence, these three groups compared with Ordinary, were statistically significant (P<0.05).(5) The prognosis when the disease12weeks of follow-up, recording changes in condition (including recurrence death, and NIHSS, BI, MRS score) to assess the relationship between physical type and prognosis, ajority constitutions in Traditional Chinese Medicine (TCM) were Yin deficiency, blood stasis and Qi deficiency in patients with recurrent stroke (Respectively25.6%,22.7%and19.2%). Results:(1) The relationship between gender and physical types:Yin deficiency common in male patients (23.5%), blood stasis (21.8%) and phlegm-dampness (20.3%); Yin deficiency common in female patients (28.0%), blood stasis (23.8%), Qi deficiency (20.8%), but the difference was not significant (P>0.05). The relationship between age and physical type:The most common types of constitution were Phlegm-dampness (40.0%,35.6%) and damp-heat mass (20.0%,15.6%) in30to50-year-old patients. The most common in patients50to60years is Yin deficiency (25.6%) and Phlegm-dampness (22.1%). The most common in patients60to70years is Yin deficiency (27.5%), blood stasis (24.8%) and Qi deficiency (20.2%) mainly70to80years and80years of age or patients with blood stasis (32.1%,35.7%), Yin deficiency (28.2%,32.1%) and Qi deficiency (24.3%,28.6%) mainly. Constitution of Phlegm-dampness and damp-heat decreased with age over40years old. Constitution of Yin deficiency, Qi deficiency and blood stasis increased gradually with age in patients. The relationship between BMI and physical types:Constitution of Phlegm-dampness were the most common type in obese and overweight patients, while constitution of Yin deficiency were most common in other patients.(3) Found that the presence of risk factors among different physical points difference, which points the lowest in patients with Ordinary, and Yin deficiency and blood stasis in patients with risk factors for recurrence points higher from the analysis. Physical type analysis found that patients with recurrent stroke risk factors in each merging Phlegm-dampness, Yin deficiency and blood stasis more, but with no significant difference in the incidence of various types of physical risk factors in patients.In our study, Most patients with hypertension, diabetes, carotid artery plaque, more than half with diabetes and carotid plaques, more than one-third of the combined. So we concluded that high blood pressure, diabetes, and carotid artery plaque were major risk factors for recurrent stroke.(4) The NIHSS physical type of relationship:nerve function defect in patients with mild interstitial light, and qi deficiency, blood stasis, Yin deficiency in patients with neurologic impairment is relatively heavy, the difference was statistically significant (P<0.05). Physical type relationship the the Barthel Index score:Ordinary BI score higher, and blood stasis, Yin deficiency, Qi deficiency in patients with relatively low scores, the difference was statistically significant (P<0.05). The relationship between physical type and MRS: Yin deficiency, blood stasis, Qi deficiency high quality of daily life dependence, these three groups compared with Ordinary, were statistically significant (P<0.05).(5) Recent follow-up of the difference between the outcomes of different types of physical dependence in daily life (MRS) in patients with admission NIHSS and BI score the12weeks of follow-up between NIHSS and BI score, no significant difference (P>0.05).Conclusion:There were more TCM constitutions of Yin deficiency, blood stasis and Qi deficiency in patients with recurrent stroke. The type of TCM constitution varied with age and weight. Hypertension, diabetes, and carotid artery plaque were major risk factors for recurrent stroke. Both neurologic impairment and damage of daily living were heavier in patients with the constitution of Qi deficiency, blood stasis, and Yin deficiency at admission compared with patients with the constitution of Ordinary, while the high dependence of everyday life. After12weeks of treatment, no significant difference in the short-term efficacy and outcomes between different types of physical medicine. |
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