Comparison Of Short-term Effect Of Video-assisted Thoracoscopic Lobectomy And Conventional Lobectomy In The Treatment Of Early Non-small Cell Lung Cancer

Objective To assess the value of video-assisted thoracoscopic lobectomy in thetreatment of non-small cell lung cancer.Methods A prospective randomized controlled trial was conducted among98casesof patients with non-small cell lung cancer between from January2009and June2013. Ofthese,75patients who underwent anatomic lobectomy and systematic lymph-adenectomywere divided randomly into video-assisted thoracoscopic lobectomy group(n=36) andconventional lobectomy group(n=39). Perioperation period indexes, laboratory indexes andquality of life between the two groups were compared.Results The amount of blood loss, post-operative drainage, ambulation time andhospital stay in the video-assisted thoracoscopic group were significantly less than those inthe conventional group (p<0.05)．The lymph node dissection, the lung cancer recurrenceand metastasis between the two groups had no significantly difference (p>0.05). Thehigh-sensitivity C-reactive protein was significantly enhanced after operation in bothgroups, but it was significantly lower in the video-assisted thoracoscopic group than inconventional one(p<0.05). The damage of pulmonary function was lessened in thevideo-assisted thoracoscopic group compared with that in the conventional one(p<0.05).The quality of life in both groups were improved after operation.Physical well-being andfunctional well-being were much better in the video-assisted thoracoscopic group than inthe conventional one(p<0.05).Conclusion Compared with the conventional lobectomy, video-assisted thoracoscopiclobectomy in those patients of early non-small lung cancer show less invasive, less damageof lung function and better quality of life.It is worth adopting this method to treat earlynon-small lung cancer.