Assesment Of Left Ventricular Twisting And Untwisting In Primary Hypertention Patients Using Speckle Tracking Imaging

Objective The aim of this study was to evaluate left ventricular twisting and untwisting in patients with primary hypertension, and to investigate their clinical significance.Methods We selected62patients with primary hypertension, including32non-hypertrophic patients and30mild hypertrophic patients, we also selected32healthy subjects as control group. Peak basal rotation, Peak apical rotation in basal and apical short-axis views were measured by speckle tracking imaging. Peak left ventricular torsion(Ptw), twist at aortic valve closure(AVCtw), twist at mitral valve opening(MVOtw) and untwisting rate(UntwR) were calculated.Results Ptw, AVCtw and MVOtw were significantly higher in patients with primary hypertension compared with control group(P<0.05), and UntwR reduced in primary hypertensive patients (P<0.05).Conclusion Left ventricular twisting is higher in primary hypertensive patients, and untwisting declined. Speckle tracking imaging may provide a new approach for evaluation of the mechanics of patients with hypertension.