Effects Of Different Intervention Therapy Of Bone Loss In Patients With Hyperthyroidism After¹³¹I Treatment

Objective:Hyperthyroidism bone loss after1311therapy in patients with different therapeutic intervention, discuss the best solution bone loss in patients with hyperthyroidism after1311therapy of bone recovery.Methods:hospital outpatient and inpatient treatment of patients with hyperthyroidism360cases,88cases have been screened DXA bone loss were randomly divided into three groups:Caltrate D+Rocaltrol (active):Caltrate D (each containing600mg of elemental calcium and active vitamin D125IU) once a day, one at a time, Rocaltrol (each containing0.25ug active vitamin D) once a day, one at a time; Caltrate D (general group):Once a day, once a piece; natural recovery group. All bone loss in patients with hyperthyroidism before1311treatment, after6and12months after the anteroposterior lumbar spine and femoral neck (L2-4) bone density.Results:1bone mineral density before and after treatment(1) women before and after treatment L2-4, femoral neck BMD changes:①active:6months of treatment L2-4, femoral neck BMD values were statistically significant change (P<0.05).12months significantly different (P<0.01).②ordinary group:6months of treatment L2-4, femoral neck BMD values were not statistically significant change (P>0.05).12months significantly different (P<0.05).③natural recovery group:treatment for6months,12months were not statistically significant (P>0.05). Femoral neck BMD values of natural recovery group postmenopausal even reduced.(2)men before and after treatment L2-4,femoral neck BMD changes:①activity groups:<50years old、male menopause treatment six months after the L2-4,femoral≥male,neck BMD values change was statistically significant(P<0.01-0.05).12months significantly different (P<0.01).②ordinary group:6months of treatment L2-4, femoral neck BMD values were not statistically significant change (P>0.05).12months significantly different (P<0.01-0.05).③natural recovery group: treatment for6months,12months were not statistically significant (P>0.05).50-year-old male femoral neck≥BMD values of the natural recovery group or even reduce,2Comparison of the results between the groups after treatment(1)6months:①active group and the normal group:active group L2-4, BMD value changes of the femoral neck are better than ordinary group, but not statistically significant (P>0.05);②active and spontaneous recovery group:active group L2-4, BMD values changed significantly better than the femoral neck natural recovery group, P <0.05;③ordinary group and natural recovery groups:normal group-0.01L2-4, BMD changes in the femoral neck than natural recovery group However, no statistically significant P>0.05,(2)12months:①active group and the normal group:active group L2-4, femoral neck BMD values were significantly superior to the ordinary improve group (P<0.05);②-0.01active and spontaneous recovery group:active The L2-4, femoral neck BMD increased significantly superior to natural recovery group (P<0.01);③ordinary group and natural recovery groups:normal group L2-4, BMD values of the femoral neck improve than natural recovery group, but no statistically significant P>0.05Conclusions:(1) bone mineral density in premenopausal women than in postmenopausal women improved significantly,50years of age compared to men over50years to improve bone mineral density significantly.(2) anteroposterior lumbar spine BMD improved significantly over the femoral neck sites.(3) BMD values intervention group improved better than those without the intervention;1311joint Caltrate D Rocaltrol treatment of hyperthyroidism and bone loss in the degree of improvement in BMD and the recovery time were better than single Caltrate D person.