Study On Four-dimensional Echocardiography Of Left Ventricular Systolic Function

Objective:To assess the left ventricular function of patients with myocardialinfarction by4D Auto LVQ,and correlation with4D strain to positioningand quantitative analysis of the infarction area and size. To explore theapplication value of left ventricular function in the patients withmyocardial infarction or myocardial ischemia to positioning andquantitative analysis of the infarction area and size by4D Auto LVQ and4D strain.Methods:Twenty subjects and thirty patients with myocardial infarctionusing4V full-volume cardiac probe and turn on Tri-plane to obtainreal-time dynamic three cardiac cycle of apical four-chamber view、two-chamber view and long-axis view of left ventricule,adjust the angleto get the best images,choice ejection fraction,the images will stop onthe end-diastolic automatically,and draw the outline of the endocardialon the three images in turn,then the picture jump to the end-systolic,stepup.The LVEDV、LVESV、EF、SV、HR were derived by RT-3PE.In4Dmode,using4V full-volume cardiac probe to obtain in the full volume real-time dynamic images on apical4-chamber views of4-6cardiaccycle,to ensure the image frame frequency is greater than the heart rateof40%,then choice the volume,start the software of the4D AutoLVQ,and put two points in the end-diastolic volume and end-systolicvolume of the endocardial,one point put on the middle of the mitralvalve ring,the other put on the apex of the endocardial.The LVEDV、LVESV、LVEF、SV、HR were derived by4D Auto LVQ.We can use4DStrain to obtain the left ventricular17segments of LS which is based on4D Auto LVQ.Take all the segments to express by the color-code ofIBE.All date use SPSS19.0to analysis.Results:1The difference for age、HR were not significant between thegroup of patients with myocardial infarction and the normalgroup.Through4D Auto LVQ compare to the normal group,the SV、LVEDV、LVESV were larger and the LVEF was lower in the group ofpatients with myocardial infarction than those of the control group,andhad statistically significant difference(P<0.05).Through RT-3PEcompare to the normal group,the SV、LVEDV、LVESV were larger andthe LVEF was lower in the group of patients with myocardial infarctionthan those of the control group,and had statistically significant difference（P<0.05).2There was no significant difference in HR、SV、LVEDV、LVESV and LVEF measured of normal group by two methods(RT-3PE and4D AutoLVQ)(P>0.05).Furthermore,There was no significant difference in HR、SV、 LVEDV、 LVESV and LVEF measured of MI by twomethods(RT-3PE and4D Auto LVQ)(P>0.05).3The decrease of LVEF and the increase of the LVEDV measured with4D Auto LVQ in MI was high negatively correlated(r=-0.720).4The17-segment LS of the patients with4D Strain were lower at thebasal、mid、apical and apex than those of the control subjects and hadstatistically significant difference (P<0.05).5The control subjects with4D Strain in the different left ventricularlevel had a regular:the left ventricular systolic peak strain of the mid islargest,the basal is minimum,the apical is in middle.Conclusions：1The left ventricular systolic function measured with4D AutoLVQ and assess the regional wall motion or myocardium deformation ofthe left ventricular function accurately.2Correlated with4D strain to positioning and quantitative analysiswith myocardial infarction or myocardial ischemia of the infarction areaand size.