The Clinical Research Of Choudongning Grain In Curing Tourette Syndrome Of Spleen Deficiency With Liver Hyperactivity

Objective:Evaluation the clinical efficacy and safety of the traditional Chinese medicine choudongning grain in curing spleen deficiency with liver hyperactivity’s tourette syndrome, and explore the relationship between the tourette syndrome and the total serum IgE’s level,and the total serum IgE level’s influence which choudongning grain in curing the tourette syndrome of spleen deficiency with liver hyperactivity generate.Methods:60cases cases tourette syndrome which are meeting study cri-teria are randomly divided into treatment group and control group30cases e-ach. The treatment group were given Chinese medicine choudongning grain; The control group were given Tiaprie Tydrochloride Tablets, a course is two month, After a course of treatment,Please observe the clinical symptoms befo-re and after treatment, total serum IgE’s level,blood routine,urine routine, li-ver function and kidney function, etc.Results:compare the total integral of two groups before and after treatment in the group, P<0.01,They have significant differences, indicating that both the treatment group and the control group have significant curative effect;Compare the total effective rate of two groups, P>0.05, they have no statistically significant difference, indicating that the overall curative effect of two groups in the treatment of TS are the same; The effective rate of treatment group in motility twitch was96.67%,and the The effective rate of control group in motility twitch are90.00%, compar the two groups, P<0.05, they have statistically significant difference, indicating that the treatment group curative effect in motility twitch is more superior than control group; The effective rate of the treatment group in voice twitch is83.33%, The effective rate of the control group in voice twitch is86.67%, compare the two groups, P<0.05, they have statistically significant difference, indicating that the control group in voice twitch is more superior than the treatment group. Before treatment, the serum total IgE’s positive rate of the treatment group is80.33%,and the positive rate of the control group is73.33%, indicating that the occurrence of tourette syndrome is related to the total serum IgE’s level; before treatment,the total serum IgE’s positive rate of the treatment group is80.33%,after treatment,it is43.33%, by comparison, P<0.05, they have statistically significant difference, indicating that choudongning grain can reduce effectively the positive rate of total serum IgE; before treatment,the total serum IgE’s positive rate of the control group is73.33%,after treatment, it is60.00%, by comparison,P>0.05,they have no statistically significant difference, indicating that tiapride tydrochloride tablets have no obvious effect on serum total IgE’s level;The treatment group has no adverse reactions, and the Safety index examination has no abnormity,indicating that choudongn-ing grain in curing tourette syndrome has no side effects, and it is safe.Conclusion:1.choudongning grain which cures the tourette syndrome of spleen deficiency with liver hyperactivity Has significant curative effect, and the overall curative effect is the same as the tiapride tydrochloride tablets; the curative effect of the choudongning grain on motility twitch is more superior than the tiapride tydrochloride tablets;While the curative effect of the tiapride tydrochloride tablets on voice twitch is more superior than the choudongning grain;2.The occurrence of tourette syndrome is related to the total serum IgE level;3. choudongning grain can reduce effectively the positive rate of the serum total IgE; while tiapride tydrochloride tablets have no obvious effect on the serum total IgE’s level;4. choudongning grain in curing the Tourette Syndrome of spleen deficiency with liver hyperactivity has no side effects, and it is safe.