Mivacurium Chloramine And Paramagnetic Contrast Atracurium During Inductionvecuronium Observation

Objective:Comparison of mivacurium and cis-atracurium for induction ofgeneral anesthesia intubation time and the onset of muscle relaxantmuscle relaxant effect.Experiments conducted in three parts, the first part of30cases ofchildren3to12years old were randomly divided into two groups of15people per group, a group with mivacurium do anesthesia induction,another group using cis-atracurium ammonium do anesthesia induction.The second part of the30cases of adult patients30-40years old, wererandomly divided into two groups, one group received mivacurium doanesthesia induction, another group using cis-atracurium do anesthesiainduction. The third part of30cases of elderly patients aged70-80yearsold, were randomly divided into two groups, one treated withmivacurium do anesthesia induction, another group using cis-atracuriumdo anesthesia induction. Monitor the use of muscle relaxant musclerelaxant onset time recording and evaluation of muscle relaxant effect. Results:However, Table2shows that mivacurium group compared withcis-atracurium group changes in hemodynamic changes compared withno significant (ie, P <0.05, statistically significant). Especially in olderpatients embodied particularly evident, which is due to histamine releaseaction of mivacurium. Studies have recommended mivacurium injectionslowly reduces the incidence of cardiovascular adverse reactions in the60S.Table3(P>0.05) indicated in the induction of general anesthesiaendotracheal intubation cis atracurium and mivacurium onset time of thesame.Table4(P>0.05), the same mivacurium cis-atracurium musclerelaxant effect.Discussion:Cis-atracurium and mivacurium as a new non-depolarizing musclerelaxants, with rapid onset of effect, though, quickly restored, noaccumulation, metabolism is not dependent on liver and kidney function,metabolites do not have muscle relaxant effects, etc. many otheradvantages. But both efficacy still affected by many factors, so in clinicalpractice should consider these factors in order to secure a more rationaluse of the drug. Conclusion:The onset time of two muscle relaxants, and the same musclerelaxant effect.