Clinical Analysis Of236Cases Of Ovarian Epithelial Carcinoma

Objective:This study retrospectively analyzed the general treatment process in patients withepithelial ovarian cancer,and for univariate and multivariate analyzes to further explorethe relevance of the prognostic factors in epithelial ovarian cancer.Methods:We collected all the patients with epithelial ovarian cancer who accepted theinitial treatment in the gynecologic of the First Hospital of Jilin University during2006to2011.We analyzed the clinical features of the disease and analyzed the correlationbetween the age,clinical stage,histological type,surgical approach,the number ofpostoperative chemotherapy and the prognosis.Results:1、The average age was52.0years old,and the peak age of onset was50-59yearsold.2、The main clinical manifestations in patients with early were symptoms ofabdominal pain(40.85%);while the clinical manifestation in patients with advancedwere gastrointestinal symptoms(69.09%).3、Univariate analysis showed that the age≥50years,had menopause,pregnancy frequency＜3times,,the number of production＜2times,advanced ency of chemotherapy＜6times,patients with poorprognosis.Age at menarche, tissue differentiation on prognosis was no significantrelationship.4、Multivariate analysis showed that the numbers of pregnancy,clinicalstage, histological type,initial postoperative residual tumor size and frequency ofchemotherapy were independent prognostic factors of epithelial ovarian cancer.Conclusion:1、The peak age of onset was50-59years old in epithelial ovarian.2、The patients who had bloating and other digestive symptoms should had a timely manner ultrasound andtumor markers such as CA125、HE4which can be used as routine screening forovarian cancer.3、Gynecological examination as an essential skills of gynecologistshould be sufficient attention.4、We can simultaneously resection of bilateral fallopiantube when we are in the operation of hysterectomy.Especially for the patients whoalready had baby and also has a family history of ovarian cancer to reduce theincidence of ovarian cancer.5、Age at menopause and production times are the riskfactors in epithelial ovarian cancer.And the age at menarche,tissue differentiation onprognosis were no significant relationship.6、 Number of pregnancies,clinicalstage,histological type,initial postoperative residual tumor size and the number ofchemotherapy can significantly affect the prognosis of epithelial ovarian cancer.