Clinical Study Of28Pediatric Patients With The Necrotic Cellulitis Of Maxillofacial Region

Objective:Through to the analysis of the28cases of maxillofacial necroticcellulitis clinical characterstics, early diagnosis and reduce misdiagnosis,reduce complications, timely and accurate treatment methods, improve the curerate.Methods: A retrospective study from November2007to November2012in the firstHospital of JiLin university admitted28pediatric patients of maxillofacialnecrotic cellulitis, to analyze their symptoms, laboratory tests, the etiologyand pathogenic bacteria, complications, length of hospital stay and thetreatment methods for analysis and research.Using paired sample mean t-test to discuss if the PLT concernshospitalization time and complications respectively. Using chi-square test,to discuss if the low PLT (＜70x109/L) could lead to a poor prognosis. Therelationship of time from the starting of symptoms of swelling to practice theincision drainage and prognosis,used paired sample mean t-test. Whether thereis influence of incision drainage surgery in the treatment of prognosis, usingPearson correlation test.Using logistic regression analysis to make certainwhich variables may be associated with complications and prognosis.Results: PLT count value have significant difference (t=-4.799, p=0.001)in have complications group and not have complications group.In hospital isalso associated with PLT (t=3.592, p=0.005). The length the starting ofthe swelling symptoms to execute of the incision drainage is correlated withprognosis (t=-3.081, p=0.027). Pearson correlation test results prove theexistence of the influence of incision drainage on prognosis.(x2=7.955p=0.027) By using the linear regression analysis, the shorter time from onset ofsymptoms to incision drainage, possible the smaller incidence of thecomplications (p=0.004). The patients who have breathing difficulties (p=0.007) and potentially system disease（p=0.034) patients are prone tocomplications than other children.As to whether patients with death as the dependent variable, and discussvarious variables influence on prognosis, the length of symptoms start toincision drainage treatment has a significant effect on the prognosis (p=0.024). Mortality of breathing difficulties patients (50%) with highmortality (10%) than that of the other patients (p=0.020).The patients withcomplications with poor prognosis than others(p=0.026).Conclusion:1. There are many atypical clinical symptoms in the patients ofpediatric necrotic cellulitis of maxillofacial region.2.The undefinedpathogenesis often associated with systemic underlying disease.3. PLT countcan be used as an important indicator. Operation should be carried outimmediately when the PLT count is too low.4. We don’t agree with overlyconservative treatment, surgical incision drainage is essential to the patientswho have severe complications, and the shorter of the time from the swellingof symptoms to a incision drainage operation, the smaller the possibility ofcomplications,and lower mortality.