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Clinical Efficacy Studies Xuefuzhnyu Decoction Coordinate Gamma Knife Treatment Of Non-small Cell Lung Cancer Of Blood Stasis Due To Qi Deficiency

Posted on:2015-03-24Degree:MasterType:Thesis
Country:ChinaCandidate:J WangFull Text:PDF
GTID:2254330428470693Subject:Chinese medical science
Abstract/Summary:PDF Full Text Request
Research objective:By through relatively objective and a recognized evaluation system, to discuss the influence of Traditional Chinese medicine compound——Xuefuzhuyu decoction.By through preliminary exploration Xuefuzhuyu decoction with gamma knife treatment of non-small cell lung cancer of blood stasis due to qi deficiency and affect the quality of life, toxicity.To provide theoretical basis and clinical evidence for the subsequent treatment.Research method:The NSCLC Patients were randomly divided into the treated group (n=30, treated With Xuefuzhuyu decoction secondary gamma knife treatment) and The control group (n=30, treated with Gamma Knife treatment alone).45days for a period to observe a cycle.Observed before and after treatment with the efficacy of the solid tumors, TCM symptom scoring, the quality of life, Karnofsky scores, etc.; Observed reactions observed safety index and bone marrow suppression, gastrointestinal toxicity. Using of SPSS18.0statistical software for statistical analysis. Results:(1) Evaluation of solid tumors, the observation group and control group by comparison, P=0.037, P<0.05, we considered Xuefuzhuyu decoction can increase the sensitivity of Gamma Knife treatment of patients;(2) The quality of life comparison, P=0.01, P<0.05, we considered Xuefuzhuyu decoction coordinate Gamma Knife treatment can improve the quality of life of these patients;(3) Compared in terms of improvement of clinical symptoms, prompted by Xuefuzhuyu decoction coordinate Gamma Knife treatment can significantly improve the clinical symptoms of the disease;(4) Compared the changes in body weight, P=0.179, P>0.05,Changes in body weight between the two groups showed no significant difference;(5)Tumor markers compared to the situation, suggesting Xuefuzhuyu decoction coordinate Gamma Knife treatment on serum tumor markers in patients with more pronounced effects;(6) Scores in terms of the behavior of state, P=0.005<0.01, we considered Xuefuzhuyu decoction coordinate Gamma Knife treatment has an advantage;(7) In the comparative safety indicators, you can think Xuefuzhuyu decoction can reduce the side effects caused by gamma knife treatment. Conclusion:Clinical efficacy studies Xuefuzhuyu decoction coordinate Gamma Knife treatment of Non-small Cell Lung Cancer of blood stasis due to qi deficiency in solid tumor efficacy of gamma knife than a simple program for the gifted, and can improve the quality of life in patients with lung cancer medicine to alleviate symptoms, improved Karnofsky scores, and can reduce the toxic side effects of gamma knife, its clinical efficacy is clear.There is a deeper value of clinical and basic research.
Keywords/Search Tags:Clinical efficacy, Xuefuzhuyu decoction, Gamma Knife program, Non-small Cell Lung Cancer
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