Research On Pregnancy Outcome After Preventing Early Threatened Abortion Intervened By Chinese Medicine

Objective:In view of the early threatened abortion after miscarriage treatment of traditional Chinese medicine continue to pregnancy, pregnancy outcome that mainly included observation of childbirth women during pregnancy, prenatal screening and prenatal diagnosis, incidence of complications related to pregnancy and childbirth complications and newborn health after traditional Chinese medicine miscarriage treatment, were retrospectively investigated and studied, providing data support for fetus safety of traditional Chinese medicine.Method:Selected threatened abortion was voluntary in the Affiliated Hospital of Chengdu University of Traditional Chinese Medicine the gynecological inpatient department, outpatient and outside the hospital medicine miscarriage postpartum women "threatened abortion medicine tocolysis pregnancy outcomes survey,202cases were collected from the survey. A retrospective analysis, the form of one-on-one, face-to-face interviews or telephone inquiries, collect the following medical information:(1) prenatal screening results, including Down’s syndrome, neural tube defects, and18-trisomy syndrome at high risk of positive samples out rate;(2) the results of the prenatal diagnosis, including amniocentesis, three-dimensional color Doppler ultrasound results;(3) pregnancy suffering from pregnancy complications, incidence of gestational diabetes, pregnancy-induced hypertension, intrahepatic cholestasis of pregnancy disease, pregnant women with anemia; childbirth complicated by polyhydramnios, oligohydramnios, the incidence of premature rupture of membranes, placenta previa, fetal abnormalities, cord around the neck, postpartum hemorrhage and other complications; weight gain during pregnancy, gestational age, mode of delivery of such information;(4) birth weight, length, adverse outcomes and other information.Results:1.202cases of women surveyed, in which a total of198prenatal screening, accounting for98.02%of those surveyed. High risk of detection of Down syndrome in4cases, accounting for the2.02%of the population of prenatal screening, one patient with prenatal DNA test is negative, four cases of women having children have no birth defects of follow-up investigation; detection of neural tube defects in high-risk and18-trisomy high-risk both cases, accounting for0.00%;2. Investigated202cases of women,198prenatal diagnosis,1case due to old age amniocentesis results showed negative, accounting for0.00%of the surveyed202women with three-dimensional color Doppler ultrasound examination to check three-dimensional color Doppler ultrasound results showed negative;3. Investigating202cases of women who suffer from pregnancy complications in32cases, accounting for15.84%of the surveyed population. Gestational diabetes, the most common disease, accounting for12.87%of the surveyed population; suffering from pregnancy-induced hypertension, intrahepatic cholestasis, pregnant women with anemia were2cases, accounting for0.99%of the survey population;4.202cases of women suffering from childbirth complications, a total of23cases, accounting for11.39%of the survey population, in which the cord around the neck is the most common, accounting for3.47%; polyhydramnios rate of0.50%, oligohydramnios, the incidence of premature rupture of membranes are0.99%, abnormal fetal position, the occurrence rate reaches2.48%, and the placenta previa incidence of1.48%, the incidence of postpartum hemorrhage was0.00%;5. The minimum weight gained during pregnancy of202women is7.00kg, the maximum is26.00kg, an average weight gain of15.597±3.570kg; The minimum childbirth pregnant weeks is32weeks, maximum is41+1weeks,<37weeks in8cases, accounted for3.96%,≥37weeks in194cases, accounting for96.04%;103cases of vaginal delivery, accounting for50.99%of the survey; Cesarean section of99cases, accounting for49.01%of the survey;6. The investigation of neonatal birth weight minimum is1580g, the maximum is4500g, and the average is3497.77±489.730g;The minimum newborn height is42cm, maximum is54cm, and the average was49.41±1.544cm; The newborns after preventing early threatened abortion intervened by Chinese medicine with normal birth weight, length, and there has no significant difference in statistic(P>0.05).7. Adverse neonatal outcomes survey huge children up to9cases, accounting for4.46%;the incidence of low birth weight children is2.98%. There are three cases of birth malformations, including hypospadias, atrial septal defect, ectopic right kidney, accounting for1.49%; neonatal death and suffocation incidence rate was0.00%;Conclusion:1.Chinese medicine treatment on patients with threatened abortion to continue the pregnancy does not increase the rate of prenatal screening high-risk;2. Chinese medicine treatment on patients with threatened abortion to continue the pregnancy does not increase the rate of prenatal diagnosis of abnormal results;3. Chinese medicine treatment on patients with threatened abortion to continue the pregnancy does not increase gestational diabetes, gestational hypertension, intrahepatic cholestasis of pregnancy, and the incidence of anemia during pregnancy;4. Chinese medicine treatment on patients with threatened abortion to continue the pregnancy does not increase the cord around the neck, abnormal fetal position, placenta previa, premature rupture of membranes, polyhydramnios, oligohydramnios, postpartum hemorrhage and the incidence of childbirth complications;5. Chinese medicine treatment on patients with threatened abortion to continue the pregnancy have no negative impact in fetal weight and length.6.Chinese medicine treatment on patients with threatened abortion to continue the pregnancy has no risk of increasing the huge children, children of low birth weight, birth deformities, neonatal death and suffocation of the incidence of adverse outcomes.