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Efficacy Of Low-frequency Repetitive Transcranial Magnetic Stimulation In The Treatment Of The Lateral Fissure Week Aphasia Of Post-stroke

Posted on:2014-01-18Degree:MasterType:Thesis
Country:ChinaCandidate:Y FengFull Text:PDF
GTID:2254330425955146Subject:Neurology
Abstract/Summary:PDF Full Text Request
In recent years, the incidence of stroke is rising at an annualrate of9%, With China’s increasing number of stroke patients has alsoincreased the incidence of post-stroke aphasia. According to the WorldHealth Organization (WHO) survey data show that recovery of aphasia oftenneed more than2years, and only20%patients can be fully restored. Thus,aphasia not only the rehabilitation process is slow, and the prognosis is alsounsatisfactory, the vast majority of patients with aphasia longterm or evenlifelong legacy ranging degree of speech dysfunction, some patients with theoutside world verbally communicative completely lost, a serious impact ontheir social skills, which greatly reduces the quality of their daily lives, inaddition, also bring huge burden of the family and society. Therefore,attracted the attention of more and more scholars at home and abroad for thetreatment and rehabilitation of patients with aphasia.There are many types of aphasia, which are not the same prognosis.Accordance with the Benson Law, aphasia can be divided into threecategories: the subcortical aphasia syndrome, the watershed area aphasiasyndrome and the lateral fissure week aphasia syndrome. The data show thatthe subcortical aphasia is generally able to recover on its own, the prognosisis good; the lateral fissure week aphasia syndrome is relatively poorprognosis. A common feature of the latter is a repeat have varying degrees ofdisorder, and the lesions are located in the lateral fissure week. According tothe specific lesilesion can be divided into:(1) Broca aphasia;(2) Wernickeaphasia;(3) Conduction aphasia. The conduction aphasia prognosis is better,Wernicke aphasia is worst prognosis. At home and abroad still the traditional language training as the main treatment, but the effects are uncertain. Inrecent years, there have been reports that the low-frequency rTMS tostimulate the brain non-dominant hemisphere is conducive to therehabilitation of stroke patients with aphasia, however these studies did notclassify aphasia.the rTMS efficacy of various types of aphasia is to beproved.Objective: In this study, clinical cases, designed to investigate theefficacy of low-frequency rTMS in early intervention in the treatment of thelateral fissure week aphasia of post-stroke patients explore the therapeuticvalue of the method.Methods: In this study, a total of inclusion after stroke lateral fissure24patients with aphasia. The combination of patients will be divided equallyinto two groups,12cases in each group: control group and rTMS treatmentgroup based on the random number table. rTMS treatment group weretreated with repetitive transcranial magnetic stimulation, stimulationfrequency to1Hz,10pulses per sequence,80each sequence, an interval of10seconds, the average stimulation intensity of40%to90%(depending onthe patient’s age, illness, tolerance of adjustment), a total of10times. Intothe group before rTMS treatment for2weeks, the incidence of12weeks oftheir ABC score, to determine its efficacy.Results:(1) rTMS treatment group and control group enrolled ABCscores was no significant difference (P>0.05).(2) rTMS treatment groupand control group in the rTMS treatment for2weeks ABC score was nosignificant difference (P>0.05); into the group of12weekend, the differencebetween the two groups was significant (P <0.05).(3) Into the group of12weekend, the ABC scores of rTMS treatment group and control group thanthe group has improved significantly, and the difference was statisticallysignificant (P>0.05), but the the rTMS therapy group improved more significantly (P <0.01).(4) Into the group of12weekend,rTMS treatmentgroup and control group improved in Figure named, Auditory comprehension,Repetition, Spontaneous speech than enter the group, which Figure namedthe most obvious improvement, followed by Spontaneous speech, Auditorycomprehension and Repetition are poor.Conclusion:(1) Early intervention of low-frequency rTMS may beheapful to the lateral fissure week aphasia of post-stroke.(2)There are nosignificant complications or adverse reactions in all rTMS treatmentpatients. It is show that the low-frequency rTMS is a safe and effectivemethod.
Keywords/Search Tags:Low-frequency repetitive transcranial magneticstimulation, Rehabilitation, The lateral fissure aphasia syndrome, AphasiaBattery of Chinese
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