The Preliminary MRA Classification And Its Clinical Research To Vertebrobasilar Dolichoectasia

BackgroudVertebrobasilar dolichoectasia (VBD)is an unknown etiology Posterior circulation vascular disease, the patient of VBD aren’t uncommon in clinical,because of the symptoms of VBD are not special, it is missed diagnosis frequently.Many doctors and scholars consider that VBD is Congenital vascular variation,and there is not necessity to deal it. Contrarily,it has High variability all along,the degree of angulation will be More and more serious, and there is relationship in the shape of VBA and the clinical manifestation.ObjectiveType the VBA thtough Nuclear magnetic resonance angiograph (MRA). And discuss the relativity in the types of VBA and clinical manifestation,studuy the hazards of VBA, provide identifiable ground for remedy and estimate of VBD.MethodsCollect the head MRI and MRA of the healthy or not people of our hospital in June2010to July2012,according to Smorke’standard of angulation ofVBD,Pico and Deng’s criterion of dilatation, there are1139patients meet the criterion. prick off50patient of VBD randomly and50ealth person Health person according to the sexuality and age.Analyse the General information and hazards in the VBD group and heaity group. Type the disease of VBD on the basis of MRA, analyse the relation in the types and clinical manifestation, discuss relationship in the incidence of VBD and patients’sexuality.Results1.Types:VBDs are Divided into4types on the basis of MRA:type’S’,’U’,’L’and screw-type, The type’S’has648cases (56.89%), type’U’has272cases (23.88%),type ’L’117cases (10.27%) and screw-type has102cases (8.96%)2. Hazards of VBD:hypertension、hyperlipoidemia and diabetes are the main risk factors of VBD (P<0.05), between Tobacco and alcohol addiction、adiposity and coronary disease have no significant relationship to VBD (P>0.05)3. Clinical manifestation:In1139patients of VBD, there are306patients (26.87%) have no symptom,694patients (60.93%) have the symptoms of megrim and headache,170patients (14.93%) have Posterior circulation infarction (epencephalon and brainstem).4patients have hematencephalon (0.35%),3patients have hydrocephalus (0.26%),51patients (4.48%) have cranial nerve compression symptoms (epileptiform neuralgia, mimetic convulsion, tinnitus, Hearing loss,et al)4. There is significant difference in the four types and the incidence of VBD (P<0.05). and the clinical manifestations have significant difference in four types of VBD (P<0.05).5. The case rate of VBD is5.21%, and Males accounted for68.92%.Conclusion1. On the basis of MRA,VBDs are Divided into4types:type’S’,’U’,’L’anc screw-type, there are otherness in the clinlcal symptom of different typs.2. The hazards of VBD are hypertension, hyperlipemia and glycuresis; Patients of VBD with clinical symptom’hazards:Type’U’, screw-type, hypertension and glycuresis3. case rate of VBD is5.21%,and Males accounted for68.92%.