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Early Therapeutic Effect Of Osteoporotic Thoracolumbar Fracture Freated With PKP: Analysis Of Influencing Factors

Posted on:2014-07-23Degree:MasterType:Thesis
Country:ChinaCandidate:Z LiFull Text:PDF
GTID:2254330425470022Subject:Surgery
Abstract/Summary:PDF Full Text Request
Objective: Analysis of Percutaneous Kyphoplasty (PKP) for the treatment of freshthoracolumbar osteoporotic Osteoporotic Vertebral Compression Fractures(OVCF)factors affecting the efficacy of early.Methods: Review of PKP applied in hospitalized patients from2011March to2013March in the Second Affiliated to Dalian Medical University for the treatment offresh thoracolumbar OVCF (preoperative time less than3weeks) of22cases (31vertebrae), statistical correlation analysis of PKP effect of compression in the treatmentof early fracture factors in fresh thoracolumbar osteoporotic vertebral data.All patients were measured before surgery, immediately on lateral radiographs ofvertebral anterior vertebral body height, vertebral, inferior vertebral front height, height,vertebral kyphosis angle (Cobb angle), calculated with a height of vertebra,compression rate and recovery rate correction of kyphosis angle, rate of spine, paindegree analysis of the corresponding time in patients with vertebral and record, thesevere pain by visual analog scale (Visual Analogue Scale, VAS) scores, and calculatethe VAS improvement rate. The incidence of neurological complications were recorded,bone cement injection volume, leakage rate, operation time, hospitalization time, andfracture incidence and statistical analysis of the results after operation.Analysis of age, anesthesia, preoperative vertebral, high compression rate,operation time, amount of bone cement leakage rate, neurological complications andintraoperative or postoperative, fracture incidence and leading edge, high recovery rateafter operation, kyphosis correction rate and improvement rate of VAS. On thepreoperative, postoperative VAS pain score, vertebral height, in the middle ofcompression ratio and Cobb angle by t test or rank sum test, multiple linear regressionanalysis of multiple factors analysis, to study various factors and after percutaneousvertebroplasty, vertebral compression of high recovery rate, kyphosis correction relationship rate and improvement rate of VAS.Results:22patients were neither intraoperative and postoperative neurologicalcomplications and found no leakage of bone cement.1, Vertebral compression rate and recovery rate:Preoperative leading edge compression ratio (20.64±3.82)%, postoperativeleading edge compression ratio (14.51±4.11)%, P=0.000; preoperative highcompression ratio (18.56±3.46)%, postoperative high compression ratio (13.55±3.18)%, P=0.000. Homogeneity of variance, P <0.05, two groups before and aftersurgery score difference exists statistically significant, and the vertebral heightrestoration was (30.34±11.21)%, copies of height restoration was (26.27±13.70)%, PKP effect of surgery vertebral, copies of a high degree of improvement has asignificant role.2,Cobb angle and kyphosis correction ratePreoperative Cobb angle of22.55°±1.26°, postoperative Cobb angle of11.32°±0.99°. Heterogeneity of variance, rank sum test, P <0.01, two groups before andafter surgery score difference is statistically significant, and the the kyphosis correctionrate (49.71±4.60)%, treatment is effective.3,VAS score and improvement ratePreoperative VAS score of8.23±0.81,3.73±0.63, postoperative VAS score.Heterogeneity of variance, rank sum test, P <0.05, two groups before and aftersurgery score difference exists statistically significant, and the VAS improvement ratewas (54.22±9.07)%, treatment is effective.4, Surgical treatment and influencing factorsVAS improvement rate=64.261-1.086×surgery former high compression ratio-2.823×preoperative Cobb angle+3.486×total bone cement+6.865×VASpreoperative score.Kyphosis correction rate=-1.080+0.507×preoperative leading edge compressionrate+1.651×preoperative Cobb angle+0.422×hurt in the day after tomorrow.High recovery rate=54.347-0.583×age+1.460×number of injuries acquired.The leading edge of the recovery rate=78.875-1.875×preoperative leading edgecompression ratio+3.165×surgery before the high compression ratio+14.866×anesthesia-0.954×length of stay.Note: The total amount of bone cement units: ml; hurt the number of acquired units: days; anesthesia:0on behalf of local anesthesia,1on behalf of generalanesthesia; hospitalization time units: days.Conclusion1,Early effective the PKP treatment fresh thoracolumbar osteoporotic compressionfractures.2,PKP early efficacy of radiographic parameters and preoperative leading edgecompression ratio, preoperative cobb angle, the number of injuries acquired, age,preoperative high compression ratio, duration of hospitalization, anesthesia correlation.3,Subjective pain in the the PKP early efficacy improvement targets preoperativehigh-compression ratio, preoperative Cobb angle, preoperative VAS score,cementless total correlation.
Keywords/Search Tags:Osteoporotic vertebral compressive fracture, Percutaneous vertebroplasty, Correlative factor, Early treatment response
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