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Research On Nonalcoholic Fatty Liver Disease Of TCM Syndrome Characteristics And Regularities Of Distribution

Posted on:2014-05-04Degree:MasterType:Thesis
Country:ChinaCandidate:Z Y ZhaoFull Text:PDF
GTID:2254330425458039Subject:Integrative Medicine
Abstract/Summary:PDF Full Text Request
Objective:Distribution characteristics of TCM Syndromes of non-alcoholic fattyliver disease than research, to explore the relationship between different TCM syndrometype and demographic data, liver function and blood lipid blood glucose index.Method:Screening with having no exclusion criteria were incorporated into thestandard and, combined with traditional Chinese medicine information, identifying thebasic syndromes of units, design of nonalcoholic fatty liver disease symptoms, signs ofquantization table, using statistical methods, such as frequency statistics, chi-square test,factor analysis, cluster analysis, analysis of variance of the data for processing, and throughthe investigation of gender, age, body mass index, determination of and liver function,blood sugar index, the basic TCM syndromes and sex, age and so on nonalcoholic fattyliver and objective refers to the relation between.Result:(1) non-alcoholic main pathological factors of fatty liver spleen deficiency,stagnation of liver-qi, for damp-heat, phlegm and blood stasis, deficiency of the kidney;through cluster analysis of six groups of syndrome type: liver stagnation and spleendeficiency, stagnation of damp-heat syndrome, qi stagnation, phlegm syndrome, liver andkidney yin deficiency, phlegm and blood stasis;(2) in patients with age NAFLD moreconcentrated in the40-50years old, the prevalence rate of male was higher than female;the degree of obesity in patients with NAFLD positive rate were positively correlated;(3)the TCM syndrome type, serum ALT and AST levels in patients with phlegm syndrome ofthe value of the highest, there were significant differences as compared with groups(P<0.05); the level of GGT to phlegm and blood stasis each node of the highest; serum TCand TG levels to phlegm syndrome was the most obvious; fasting blood glucose levels todamp heat retention increased significantly, followed by liver and kidney yin deficiency;(4) the constitution of traditional Chinese medicine ’s top four patients with NAFLD were as follows: heat, phlegm dampness, Qi deficiency, Qi quality.Conclusion: Patients with nonalcoholic fatty liver disease in40-50years oldmiddle-aged people see more, and more men than women. Most patients with NAFLD areoverweight, accompanied by increased blood lipids, blood glucose, liver function andblood lipid levels to phlegm syndrome increased significantly, that phlegm factors mayexist in the inflammatory activity of liver cell stage, elevated fasting blood glucose inpatients with stagnation of damp-heat syndrome of damp-heat, explain in insulinmetabolism disorder patients. Through cluster analysis of syndromes that nonalcoholicfatty liver disease basically has six kinds: liver stagnation and spleen deficiency, stagnationof damp-heat syndrome, qi stagnation, phlegm syndrome, liver and kidney yin deficiency,phlegm and blood stasis; pathological factors are spleen, liver, kidney, damp-heat, phlegmand blood stasis; disease mainly in in the spleen, liver and kidney. Heat is the most commonpathological constitution of NAFLD.
Keywords/Search Tags:Nonalcoholic fatty liver disease, TCM syndrome type, Objective index
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