Study On The Relationship Between TCM Syndrome Types Of Nonalcoholic Fatty Liver Disease And Serumfcrritin And Blood Lipid

Objective:To investigate the clinical value of serum ferritin and serum lipid in the diagnosis of nonalcoholic simple fatty liver disease,And to observe the correlation between thevalue and the TCM syndrome type and the ultrasonic grading index of non-alcoholic fatty liver disease.Methods:150 patients with NAFL and 30 healthy peoples were collected from the second people's Hospital of Fujian Provinceand physical examination center of Hospital from February 2016 to February 2017.The clinical data of the patients were collected,including name,sex,age,body mass index(BMI),liver function,ferritin,blood lipid,fasting blood glucose and so on;Color Doppler ultrasound diagnosis of fatty liver ultrasound classification,in accordance with the 2011 formulated the non alcoholic fatty liver disease diagnosis and treatment of traditional Chinese and Western Medicine Consensus" for TCM syndrome differentiation.The correlation between the indexes of ferritin,serum lipid and NAFL TCM syndrome type and fatty liver ultrasonic grading was analyzed.The statistical data were processed with SPSS 180 software.Results:1,There was significant difference in serum ferritin(SF)between different TCM syndromes and normal control group(P<0.05),Phlegm and blood stasis of SF(395.17±64.69)the highest,followed by phlegm(283.98 ± 72.80),rdhs(273.27±66.36),spleen deficiency(245.93±72.24),Qi Stagnation(228.64±68.24),normal control group(185.41±56.11).Phlegm and blood stasis group and liver qi stagnation group,liver stagnation and spleen deficiency group,the differences were statistically significant(P<0.05);phlegm dampness group and qi stagnation group,liver stagnation and spleen deficiency group,the difference was statistically significant(P<0.05);heat accumulation group compared with liver qi stagnation group,the difference was statistically significant(P<0.05);In addition,ultrasound grading distribution trend of 5 types were significantly different(P<0.001).Liver qi stagnation,liver stagnation and spleen deficiency syndrome of fatty liver showed mild(60%,46.7%);phlegm(40%);and the endoretention of damp heat,phlegm and blood Stasis of fatty liver showed more severe(46.7%,60%).2,Using Pearson correlation analysis,The mean value of SF was compared between the three groups:normal,mild,moderate and heavy,the difference was statistically significant(F=47.864,P<0.001).The SF value increased with the aggravation of fatty liver.3,NAFL different TCM syndrome type TG mean comparison,the difference was statistically significant(P<0.05),PhlegmTG value(2.28 + 0.63)is the second highest,endoretention of damp heat(2.08±0.51),phlegm and blood stasis(1.89 + 0.64),QiS tagnation(1.88+0.71),spleen deficiency(1.66 ±0.76).Phlegm dampness and phlegm and blood stasis group and liver qi stagnation group,liver stagnation and spleen defi ciency group,the differences were statistically significant(P<0.05);heat accumulation group compared with liver stagnation and spleen deficiency group,the difference was statistically significant(P<0.05);Compared with the LDL-C value of the TCM syndro mes,the difference was statistically significant(F=2.482,P=0.046),Phlegm and blood stasis of LDL-C(3.59 ±0.87)the highest,followed by phlegm(3.56 ± 0.97),rdhs(3.26 ± 0.85),spleen deficiency(3.18 ±0.88),Qi Stagnation(2.97 ±0.95).Phlegm and blood stasis group and liver qistagnation group differences were statistically significant(P<0.05);Heat accumulation group and qi stagnation group differences were statistically significant(P<0.05).Conclusions:1,NAFL different TCM syndrome types of serum ferritin,serum lipids,serum ferrit in,serum lipids contribute to the syndrome differentiation of traditional Chinese and Western medicine to provide an objective basis for prevention and treatment of NAFL.2,Serum ferritin was significantly correlated with NAFL ultrasound classification,serum ferritin could be used as an assistant index to judge the severity of NAFL.