Comparative Study Of Non Calcified And Calcification Of Fungal Inusitis’ Clinical Data And Trace Elements In Samples

Objective: According to lesions density in CT imaging examination ofnoninvasive fungal sinusitis patients, we divided noninvasive fungalsinusitis patients into calcification group and non calcified. By studyingtwo groups of patients with fungal species, trace element, lesions densityvalue in CT imaging and fungi susceptible factors, we preliminarystudied on the possible risk factors of calcification of noninvasive fungalsinusitis. Methods: Chose the2008January to2012July in Ya’anPeople’s Hospital otolaryngology inpatients, according to the standard ofinclusion and exclusion, through the pathological diagnosis and imagingdiagnosis, divided noninvasive fungal sinusitis patients into calcificationgroup and non calcified, collected the cases’ general clinical data,preoperative endoscopic sinus examination results, medical imaging data,operation data, surgical specimens, pathology results, analyzed thespecimens’ trace elements. The specimens were subjected tohistopathological examination; Patients were followed up for more thanhalf a year. The main methods:⑴Correlation factors were investigatedby using the multiple factor Logistic model regression analysis. Found out the most relevant factors associated with noninvasive fungal sinusitiswhich showed calcification spots or points in CT images.⑵For thepatients which lesions located in maxillary sinus of non-invasive fungalmaxillary sinusitis, according to the CT imaging and operation video data,Determined and accounted the data of natural ostium of maxillary sinus.Chi-square test was used to compare the difference between two groupsof patients with natural ostium of maxillary sinus.⑶determined twogroups of specimens from patients with the content of calcium,magnesium, iron, phosphorus. By atomic absorption spectrometry and themolybdenum blue method, drew standard curve regression equation lists,compared two groups of specimens in the content of calcium, magnesium,iron, phosphorus. Results:⑴According to this result, a predictiveequation was built. The Logistic regression predictive equation of fungalrhino-sinusitis was: y=-1.150+2.215X1+2.523X2-1.151X3， P＝exp(y)/[1+exp(y)] in which the concomitant variables were course ofdisease(X1), haem-nasal discharge(X2)，Susceptible factors(X3). The Pvalue means the probability of exposing calcification. All the data ofinvolved patients were analyzed with the equation, those who got P>0.50in calcification group occupied87.1%, while in non calcification group,the proportion of patients who got P>0.50was just13.5%.⑵Two groupsof patients with maxillary sinus congestion contrast analysis showed:Calcification group sinus occlusion rate was85.42%, non calcification group sinus occlusion rate was63.89%. χ2=5.2555,P＜0.05. Two groupsof cases with ostium of maxillary sinus difference was statisticallysignificant.⑶T test was used for comparison of the measured values oftrace elements of calcification group and non calcification group ofnoninvasive fungal sinusitis specimen: t values of Calcium, magnesium,iron, phosphorus were11.0256,24.3751,4.4872,9.1091, P <0.05.Difference in the two groups has statistical significance. Conclusions:⑴Probability of show calcification in CT image of noninvasive fungalsinusitis patients is relate to the cause of disease, haem-nasal dischargeand fungal predisposing factors, which course of disease and haem-nasaldischarge were risk factors, and fungal predisposing factors wereprotective factors.⑵The probability of maxillary sinus occlusion incalcification group is higher than that of non calcified.⑶The content ofthe trace elements measured in the experimental group of fungispecimens is higher than the control group.