| Objective: Multislice computed tomography (ct) imaging (multi-spiral computed tomography, MSCT) quantitative of post-processingtechnique in diagnosis of pneumoconiosis observation object value, and thepost-processing of quantitative determination of technical data and clinicalpulmonary function,(pulmonary function test, PFT) for the determinationof index correlation analysis between them.Materials and Methods: To use GE LightSpeed16-CT scanner tostudy:(1) selection is provided by the centers for disease control inchongqing by the high kv chest radiograph diagnosed pneumoconiosisobservation object of coal dust, silica dust contact with60cases, diagnosticcriteria for the diagnosis standard of the People’s Republic of Chinanational occupational health standards (GBZ70-2009), as a team;(2) select40men as control group, no dust exposure history, conventional X-raychest radiography and clinical cardiopulmonary function without damagethe health of the male as the normal control group. Two groups of subjectssigned informed consent form. Pneumoconiosis observation group ofobjects are doing clinical pulmonary function examination,(pulmonary function test, PFT). Two groups in the image post-processing workstationfor quantitative determination of data; The last object of pneumoconiosisobservation group of measurement data and clinical pulmonary functionexamination index correlation analysis.Results:1.MSCT post-processing techniques of pneumoconiosis quantitativeobservation object different anatomical level:(1) Aortic arch roof, tracheal subcarinal6cm level, level2observation in10-832--352hu CT threshold range, pneumoconiosis pixelindex (PI) of the observed group were higher than normal control group.(2)Tracheapromontory,subcarinal3cmlevel,level2observationin11-880--880hu CT threshold range, pneumoconiosis pixel index (PI) ofthe observed group were higher than that of normal controls.(3)Aortic arch roof, trachea, lung, trachea subcarinal3cm,6cmsubcarinal four observation level, level in10-832~352HU, range,pneumoconiosis pixel index (PI) of the observed group were higher than innormal control group. With grid line according to statistical results,pneumoconiosis observation object pixel index distribution curve, graduallymoving to the right, and CT to the high value area of migration.2.MSCT post-processing techniques of pneumoconiosis quantitativeobservation object the lungs:(1)Pneumoconiosis observation group of objects in11CT-880-- 352HU values within the range of pixel index (PI) were higher than normalcontrol group, the difference was statistically significant (P <0.05).Compared with normal control group, the pneumoconiosis observationobject set of PI distribution curve to offset high CT value area, shows theaverage lung density increased. Two groups-1024~976HU, HU-976--976,-928~880HU, the three range pixel index (PI), there was nostatistically significant difference (P>0.05)3.Pneumoconiosis observation object group post-treatment quantitativemeasure indicators and clinical pulmonary function examination correlationanalysis between them:(1) Pneumoconiosis observation group of objects-1024~352HU,CT value threshold range, average pulmonary lung density value and clinicalpulmonary function examination, pulmonary function test, PFT) indexforced vital capacity (FVC) and forced expiratory volume in1second(FEV1.0) are negatively correlated (P <0.05), the difference has statisticalsignificance. Results show that: pneumoconiosis observation object groupmean lung density value is inversely proportional to the clinical lungfunction index, shows that the mean lung density value, the greater the lungfunction damage is more serious accordingly.Conclusion:1. CT digital quantitative analysis, it is a direct quantitativemeasurement method of non-invasive, not only a visual assessment is more accurate, and can reduce people’s differences.2. MSCT post-processing quantitative techniques of quantitativeindicators can understand pneumoconiosis observation object to a certainextent, process of early pulmonary fibrosis.3. MSCT post-processing technology research pneumoconiosisobservation object, quantitative examination is convenient, strongrepeatability, can form, quantitative, locate the three balance.4. MSCT post-processing quantitative techniques of quantitative indexand clinical pulmonary function examination index correlation analysisbetween them, can reflect the degree of impaired lung function. |
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