Font Size: a A A

Relevance Factor Analysis Of Endometriosis Recurrence After Operation Treatment

Posted on:2014-11-14Degree:MasterType:Thesis
Country:ChinaCandidate:X H YangFull Text:PDF
GTID:2254330401980165Subject:Obstetrics and gynecology
Abstract/Summary:PDF Full Text Request
Objective: Collect clinical data, statistical analysis of the recurrence rate and relatedfactors of recurrence, to provide clinical basis of therapeutic measures for reducing thetreatment of endometriosis following conservative surgey recurrence. Methods:Retrospective study of358cases with operative treatment of endometriosis patientsBetween January2008and June2012in the First affiliated hospital of xinjiang medicaluniversity. Detailed records of the clinical data of patients with a total of28factors,including the general conditions (nation, age, body mass index (BMI), menstrual history,abortion times, cesarean delivery times, EM diagnosis course for the first time),perioperative conditions (gynecologic examination B ultrasonic examination operativetime surgical options r-AFS postoperative pathologic stage postoperative medication)and postoperative pregnancy time assisted reproduction way CA125levels afteroperation oral contraceptives after operation, ect. Analysis of endometriosis recurrence ofpostoperative recurrence rate and related factors. All datas input SPSS17.0statisticalsoftware for analysis. Results: the endometriosis postoperative recurrence rate was16.5%(59/358), including cumulative recurrence rate was11.5%(41/358) in conservativesurgery in4years; cumulative recurrence rate4.2%(15/358) in half radical surgery in4years; cumulative recurrence rate was0.2%(1/358) in radical surgery in4years. ByMulti-factor unconditional Logistic regression analysis show, factors affecting the risk ofendometriosis recurrence: Onset age for the first time, preoperative medication, the choiceof operation time, surgical procedure, r-AFS staging, pathological type, clinical drugtreatment after operation, Maternal time after operation and stimulate ovulation helppregnant time after surgery,(chi square values respectively were8.986、6.076、5.076、32.076、28.215、35.021、12.045、7.251、6.076, and P<0.05). Conclusion: Related factorsof Onset age for the first time, preoperative medication, the choice of operation time, surgical procedure, r-AFS staging, pathological type, clinical drug treatment afteroperation, Maternal time after operation and stimulate ovulation help pregnant time aftersurgery. Therefore, dealing with the young, after the vault Tenderness nodules, III-IVperiod patients with postoperative medication, may reduce postoperative recurrence.Postoperative treatment recommended GnRh-a for6months. Total hysterectomy is morehelpful than subtotal hysterectomy in half radical patients. Recurrence after radical surgeryis very low, but because surgery may lead to some discomfort symptoms for a long timesome for low estrogen levels. so according to symptoms to use hormone replacementtherapy (HRT), but after the preparation before must make a comprehensive assessmentand close follow-up.45and older patients regardless of what surgical treatment,postoperative does not need combination for the prevention of recurrence. Postoperativepatients with fertility requirements should be actively assisted reproduction after surgery.
Keywords/Search Tags:endometriosis, recurrence, Related factors
PDF Full Text Request
Related items