Zhu Jiangui Insomnia Diagnosis And Treatment Experience Of Clinical Studies

Objective:Evaluation Zhu Jiangui insomnia diagnosis and treatment experience of clinical curative effect and its related influencing factors of insomnia treatment efficacy.Methods:Collection in March2012to April2012visits in China academy of sciences hospital gate geriatrics department outpatient service of traditional Chinese medicine, conforms to the diagnostic criteria of traditional Chinese medicine (TCM) and western medicine diagnostic criteria and the three type of traditional Chinese medicine syndrome differentiation standard,120patients divided into treatment group and control group30people to90.Syndrome differentiation and treatment of treatment group was given Zhu Jiangui professor liquid form, the control group gives the gate hospital hospital preparations zizyphus jujube kernel paste treatment for28days. Were observed and recorded before treatment, treatment for14days and28days Pittsburgh sleep quality scale of the change of the integral, and observation of patients with different age, different course of Pittsburgh sleep quality scale scores of change.All data through SPSS16.0statistical software analysis, evaluating the effect of herb tea treatment based on syndrome differentiation of traditional Chinese medicine treatment of insomnia, the influence of different course, age and the relationship between the treatment curative effect.Results:Will complete the treatment course of this study,120cases of patients as observation object, the treatment group of90people, the biggest86years old, smallest,31,18cases mean age54.88±11.25years old, male, female72cases, the average duration of61.11±68.14months;30cases of control group, the biggest77years old, smallest,31, mean age55.70±11.96years old,3were male, female,27cases, the average duration was64.10±73.49months. By T test analysis, there were no statistical significance (P>0.05).The overall curative effect comparison. Research shows that traditional Chinese medicine syndrome differentiation and treatment and proprietary Chinese medicine treatment for14days and28days had statistical significance (P<0.05). Overall, at the end of the two period of treatment has a therapeutic effect. Compare two course of PSQI score before and after the difference of the mean, averages6.31±2.97a treatment for28days,14days of treatment mean was3.9±2.99. The difference was statistically significant between them (P<0.05). The curative effect of treatment for28days is better than the treatment for14days.Curative effect in treatment group and control group comparison.14days after treatment, the treatment group of PSQI before therapy and after therapy integral mean difference of4.66±2.87. PSQI in the control group before treatment and after treatment integral differential value of the mean was1.63±11, examined the rank and the difference between the two groups was statistically significant (P<0.05). The14days after treatment, the treatment group is better than the control group. Treatment after28days before the group of PSQI score and the treatment of PSQI score difference mean was7.22±2.56, the control group after treatment of PSQI score and treatment before the PSQI score difference mean was3.60±2.42. The nonparametric test the difference between the two groups was statistically significant (P<0.05). Namely,28days after treatment, the effect of treatment group is better than the control group. Observation of treatment group and control group in14days and28days after treatment of Pittsburgh sleep quality score of seven factors (sleep quality, sleep time, sleep time, sleep efficiency, sleep disorder and daytime dysfunction) mean. After nonparametric test, the treatment group and control group14days and28days after treatment in sleep efficiency improved integration between the two groups have no statistical significance (P>0.05). Other sleep factor comparison between the two groups have statistical significance (P<0.05). Treatment group after treatment for14days and28days after treatment the scores of seven factors reduce the mean differences are greater than the control group. Treatment group before treatment and after treatment the scores of each quality factor lower too. Control group14days and28days after treatment difference reduces the amplitude is smaller. Treatment group compared with control group in addition to sleep efficiency P values not significant, other quality factors of the comparison between the two groups have statistical significance. Suggests that the treatment group can better alleviate patients with insomnia.Dialectical treatment group compared with control group curative effect. The syndrome differentiation and treatment of three groups (group heart kidney is not handed in, phlegm fire one heart, liver and spleen discord group), respectively, and treatment control group to observe the curative effect in the group if there is a difference. Each group30patients. Treatment for14days after heart kidney is not handed in group of PSQI-PSQI therapy before the difference mean was4.00±2.51, phlegm fire disturbing group mean was4.60±3.15, liver and spleen discord group mean was5.36±2.83, the control mean was1.63±2.10. The nonparametric test, between the four groups of PSQI score difference was statistically significant (P<0.05), the dialectical treatment group is better than the control group. Treatment group28days heart kidney is not handed in PSQI-before the PSQI therapy after treatment the difference mean was6.80±2.52, phlegm fire disturbing group mean was7.63±3.13, liver and spleen discord group mean was7.23±1.92, the mean was3.60±2.41in the control group. The nonparametric test between the four groups of PSQI score difference was statistically significant (P<0.05), the dialectical treatment is better than the control group. Were followed three dialectical comparison of two treatment groups, the least significant difference t-test analysis, various dialectical curative effects between the treatment groups has no statistical significance (P>0.05).Comprehensive comparison of curative effect. Overall comprehensive curative effect compare to clinical recovery, powerfully, valid and invalid as observation index.14days after treatment, the overall clinical healing for1case,22cases had marked effect,25effective,72had no effect, total effective rate was40%.28days after treatment, clinical healing in2cases,45cases,41cases were markedly effective, ineffective32cases, total effective rate was73.3%. Comprehensive, curative effect is superior to the28days14days treatment. Compare the comprehensive efficacy of treatment group and control group.14days after treatment, the treatment group clinical recovery in1case,22cases were markedly effective, effective19cases,48cases. The total effective rate was46.6%. Control group clinical recovery0cases,0cases were markedly effective,6cases effective, invalid24cases. The total effective rate was20%. Total effective rate in treatment group than the control group, the difference was statistically significant (P<0.05).28days after treatment, clinical healing in2cases, the treatment group45cases were markedly improved,28cases,15cases were ineffective, the total effective rate was83.3%. Control group clinical recovery0cases,0cases had marked effect,13cases of effective,17had no effect, total effective rate was43.3%. Treatment group total effective rate was higher than the control group. The difference between the two groups was statistically significant (P<0.05).Course of the disease’s influence on the curative effect. The clinical course of patients can be divided into five layers:12months,1,1-2,12to36months, months3,36-72,4,72-120months,5,120-360months. Statistics of each layer of the14day after treatment and clinical heal,28days after treatment, effective and invalid cases were markedly improved. Through statistics shows the efficient levels of14days after treatment, respectively,75%,35%,40.7%,14.2%,6.6%。 By the rank and test analysis, the treatment effect between each course’s difference was statistically significant (P<0.05). High efficient course in under12months. Treatment of28days each hierarchical efficient were88.8%,70%,85.1%,57.1%,85.1%. By the rank and inspection analysis, explain each layered treatment curative effect difference was statistically significant (P<0.05). High efficient course in under12months.The effect of age on. The patient’s age is divided into5groups,31-42,42,53years old, aged53-64,64-75years old,75-86years old. Respectively, observe clinical recovery from all age groups, takes effect, the number of valid and invalid, and calculate the efficiency of each age groups. By the rank of two groups of level data and test analysis of all age groups and the curative effect of don’t think it was statistically significant difference (P>0.05). That is associated with treatment the effect not think different ages.Conclusion:1application treatment based on syndrome differentiation of TCM curative effect is superior to the proprietary Chinese medicine cream of semen ziziphi spinosae (zs). TCM syndrome differentiation and treatment of patients with sleep improved especially.2the doctor of traditional Chinese medicine syndrome differentiation and treatment of insomnia in28days curative effect is distinct, prompt application of traditional Chinese medicine syndrome differentiation and treatment of insomnia should be adequately extended period of treatment, in conformity with the research results of modern medicine.3The comparison between the3three dialectical way without statistical significance. Consider related to fewer cases of this group. in the future research can expand the sample size accordingly. in order to get more objective results of the study.4Comparison between curative effect and course of the disease was statistically significant (P<0.05), shorter course of treatment the shorter the time had marked effect, and the higher efficient.5Different age groups and the curative effect is no statistical significance. Consider the study of traditional Chinese medicine from China academy of sciences geriatrics collection of cases, the patient’s age concentrated in42-75, future research may consider from different locations included patients of all ages.6Observation time is shorter, comparing the status of the two groups of recurrence has not yet been concluded that the long-term curative effect of TCM syndrome differentiation and treatment for patients with insomnia and the influence of the recurrence, still needs further clinical research.