Clinical Observation Of Modified Xiaochaihutang And Indomethacin Suppository Treat Carcinoma Fever Of PLC

Objective：According to clinical observation of treatment effect of the group of indomethacinsuppository and the group of modified xiao chaihu tang combined with indomethacinsuppository for treating liver cancer fever, we can compare symptoms of before and aftertreatment.From the result,we can find a more effective method for liver cancer fever,andmeanwhile,it can reduce comsumption of the disease on the body and improve the quality oflife.Method：From the patients who was diagnosed with liver cancer in first affiliated hospital ofshehezi university from January to December2012(according to the2011specification fordiagnosis and treatment of primary liver cancer),we choosed the sixty patients with carcinomafever.Sixty patients was randomly divided into two groups of30.The two groups were treatedrespectively with indomethacin suppository, modified xiaochaihutang combined withindomethacin suppository. Xiao chaihu tang was given twice a day warmly(at10o’clock inthe morning, and at2o’clock in the afternoon) and indomethacin suppository was givenrectally,each100mg,up to once daily when patients’temperature was higher than37.3℃.When the patients’ temperature returned to normal,they still needed to be proceed with thetraditional Chinese medicine dialectical therapy until their spirit,appetite and sleep return tonormal about one or two weeks,but they no longer needed indomethacin suppository.Recording the temperature change before and after administration. If the temperature dropedto normal in five days,it could be recorded as an valid.At the same time,if the temperature washigher than37.3℃in five days,recorded as invalid. From the result we could get scientificand objective evaluation of the efficacy of the two groups.Results:1In the group of the thirty patients treated with modified xiaochaihutang combinedwith indomethacin suppository,there were twenty five patients whose temperature returned tonormal in five days. The effective rate is83.33%. In the group of the thirty patients treatedwith indomethacin suppository,there were seventeen patients whose temperature returned tonormal in five days. The effective rate is56.67%.χ2=5.079,P=0.047.The result shows astatistically significant between two groups.2Comparison the onset time of the two groups of drugs:Accroding to the rank sum testof two independent samples,The median onset time of group of modified xiaochaihutangcombined with indomethacin suppository is3days. The median onset time of group ofindomethacin suppository is4days, P=0.00.The result shows a statistically significantbetween two groups.Conclusion：1The effect of group of modified xiaochaihutang combined with indomethacinsuppository is better than the group of indomethacin suppository.2The onset time of group of modified xiaochaihutang combined withindomethacin suppository is earlier than the group of indomethacin suppository.