Analysis Of Etiological Factor And Correlative Factors Of Lower Gastrointestinal Bleeding

Objective: To investigate the composition of etiological factors in LGIH and therelationship with concerned factors such as age and sex.To explore the diseased regionsin the patients of LGIB caused by common etiological factors.Methods: Collect the patients with LGIB in the Second Affiliated Hospital ofDalian Medical University from January,2002to December,2011and select124caseswith definite causes to perform statistical analysis on their clinical data. According tothe age, the patients were divided into older age-group, middle-aged group and younggroup. To clarify whether there exist the differences or not among them by comparedthese three groups. Moreover, the patients were also divided into male group and femalegroup according to the sex. To compare the causes between this two groups and torealize whether there are differences between them. To compare the predilection sitesamong the patients with large bowel neoplasm,colorectal polyp and colonic vascularmalformation respectively and to detect whether there are differences among them.Results:1. The major causes of LGIB were31cases of intestinal tumors (25.0%),25casesof intestinal vascular malformations (20.2%),18cases of perianal disease (14.5%)(including16cases hemorrhoids,2cases of anal fissure),14cases of colorectal polyps(11.3%),11cases of colonic inflammation (8.9%),7cases of intestinal diverticulum(5.6%),7cases of ischemic bowel disease (5.6%),5cases of inflammatory boweldisease (4.0%),4cases of solitary ulcer (3.2%), and the other2cases(1.6%) comprise theportal hypertensive enteropathy and the terminal ileum anastomotic bleeding afteroperation (p<0.05).2. The ratio between the patients from the older age-group to the all LGIH patientsis the highest(58.0%), followed by the young group (21.8%) and the least was the middle-agedgroup (20.2%)(p<0.05). 3. The percentage of the male LGIB patients (54.03%) was more than femalepatients (45.97%), while there is no statistical significant differences (p>0.05).4. The predilection sites of these LGIB patients caused by large bowel neoplasm(25.0%) were rectum (33.3%) and the transverse colon (22.2%), respectively.(P>0.05).5. The predilection sites of these LGIB patients caused by colorectal polyps(11.3%)were rectum (4.9%)(P>0.05).6. The predilection sites of these LGIB patients caused by colonic vascularmalformations (20.2%)were ileocecal junction (19.0%) and ascending colon(19.0%), respectively.(P>0.05).Conclusions:1. The main etiological factors of LGIB were intestinal tumor, colorectal polyp,anal canal disease, intestinal vascular malformations, inflammatory bowel disease andso on.2. The LGIB is related to age factors. The main etiological factors in the younggroup were colorectal polyps and intestinal vascular malformation hemorrhage. Themain etiological factors of the middle-aged group were perianal disease and in the olderage-group were intestinal tumor hemorrhage.3. The LGIB is also related to sex factors. The incidence of intestinal tumor,colorectal polyp, intestinal vascular malformations in male are higher than those of infemale, while the incidence of perianal colonic disease, inflammation and ischemicbowel disease in female is higher than that of in male.4. The most common predilection sites in colorectal tumor were the rectum andtransverse colon. The most common predilection sites in colorectal polyp were therectum. And the ileocecal junction and ascending colon contributed to the mostcommon predilection sites for colonic vascular malformations.5. The colonoscope is economical and reliable method for diagnosing LGIB.