The Clinical Analysis Of Borderline Ovarian Epithelial Tumors In26Cases

Objective: Exploring the clinical pathologic features,management and prognosisof borderline ovarian epithelial tumors.Methods: By retrospective investigating, the clinical data of26patients withborderline ovarian epithelial neoplasm tumors who had operation in our hospital in2002.1-2012.1display below, he main clinical pathologic features, serologicalexamination before operation, exploring the tumors and abdominopelvic cavity duringthe operation, frozen section pathological results in the operation, treatments(conservative surgery or radical surgery), pathology results after operation, the follow-up therapy (second surgery, chemotherapy after surgery,etc), recurrence and metastasis.Results:11patients were serous borderline ovarian tumor (42.3%);15patients weremucious borderline ovarian tumor (57.7%).21cases were abdominal bulge orabdominal mass,which is the common symptom of borderline ovarian tumors,4caseswere found by health examination,9cases were vaginal bleeding and urinary systemsymptoms.In the26cases of BOT patients,22patients did CA125inspection before theoperation,13cases had the positive result of CAl25(59.1%),16cases did CA199inspection,5cases had the positive result of CAl99(31.3%).21cases did CEAinspection,6cases had the positive result of CEA (28.6%).16cases did AFP inspection,no positive cases. In the operation,the size of the tumors were3.0-35cm. Involvementovarian side:21cases occur in the one ovarian,5cases in the both ovarian. The ovariantumors affiliate ascites occur in5cases,2patients did cytological examination ofascites,no cases found tumor cells. During the operation,21cases did quick frozenpathological inspectors,5cases do not,18cases had the same result with postoperativepathological inspectors, which accuracy rating was85.7%.The clinical stages:21caseswere phaseⅠ(80.8%),5cases were phaseⅡ(19.2%). The most important treatment ofthe ovarian borderline tumors was surgery. During the26patients,5cases had the standard management of epithelial ovarian cancer,21cases had conservative surgery.1cases had pelvic lymph node dissection, no positive result of lymph nodes.2patients(including1cases of phaseⅠand1cases of phaseⅡ)followed by adjuvantchemotherapy.adjuvant chemotherapy There was a single drug like cisplatin,combination chemotherapy like cyclophosphamide+carboplatin and paclitaxel pluscarboplatin.20patients were follow-up in26cases and6cases were lost,20patients’follow-up times were2months-81months,one death.Conclusion: the disease incidence in mucious borderline ovarian tumor is higherthan in serous borderline ovarian tumor; quick frozen pathological inspectors have highaccuracy in diagnosing ovarian tumor that has great value to gynecologist; the mostcommon treatment of ovarian borderline tumor is surgical treatment; during the youngor having fertility requirements of early ovarian borderline tumour patients,conservative surgery is effective and feasible; follow-up is warranted, especially for thepatients who have high risks of recurrence.