Meta-analysis Of Fertility Preserving Surgery In Early Stage Cervical Cancer

[Objective] Analyse the comparison of early cervical cancer patients underwent fertility-sparing radical trachelectomy with radical hysterectomy in the aspect of operative time, blood loss, postoperative recovery time, intraoperative complications, recurrence rate, mortality rate.[Method] A systemically search of the literatures were performed of both prospective and retrospective studies, extract data for meta-analysis fowlled.[Result]7studies were included in the meta-analysis. Radical resection of cervical (RT) group and radical hysterectomy group (RH) group are compared in postoperative hospitalization time P<0.05, has statistical significance; operation time P>0.05, no statistical significance; amount of bleeding during surgery P>0.05, no statistical significance. NO complication odds ratio(OR)between RT and RH was0.94,95%CI was0.85-1.94,but there is publication bias. NO recurrence OR between RT and RH was0.99,95%CI was0.95-1.02. There were no statistical differences. Survival OR between RT and RH was0.98,95%CI was0.95-1.02. There were no statistical differences.[Conclusion](1)Radical trachelectomy (RT) is superior than radical hysterectomy (RH) in the aspect of postoperative recovery time. However both techniques shows no significant difference in operative time and blood loss, therefore in conclusion radical trachelectomy shortens hospital stay, and promotes rapid postoperative recovery(2) There is no significant statistics difference in recurrence rate and mortality rate, hence indicating that the radical trachelectomy (RT) and radical hysterectomy (RH) have the same occurrence in the relapse rate and mortality rate.(3)There is no statistical significance in intraoperative complications, but due to the presence of publication bias, hence requires more RCT experiments to confirm this representation.