Correlation Study Between Bone Mineral Density Values And The Level Of Estrogen After Intertrochanteric Fracture Of Elderly Male

Objective To find how the level of estrogen, which is produced after the operation of intertrochanteric fracture of femur in elderly men, affects the bone mineral density and the healing effect to Osteoporotic fracture. The achievement can guide the further study on treatment about Osteoporotic fracture after operation.Methods To collect47elderly men patients who accepted the operation remedy for intertrochanteric fracture of femur and hospitalized in department of orthopedics of Affiliated Hospital of Hebei University from January to December in2012. Based on Osteoporosis Diagnosis Standard recommended by WHO, the collected cases are classified into3groups:18cases in osteoporosis group(T<-2.5);17cases in bone weight deduction group(-2.5<T<-1.0) and12cases in non-osteoporosis group(T>-1.0). All the patients are operated by PFNA and tested the level of estrogen and bone mineral density on the1st day of hospitalizing, the3rd day after operation, the14th day after operating and the45th day after operation. The collected data are analysied by the use of SPSS16.0statistical software. The statistics processing date all indicated in the form of Mean±Standard(x±s). The comparison of enumeration data uses repeated measurement variance analysis. There was a statistically significant(P<0.05) and correlation coefficient shall be analyzed by Pearson method.Result Statistical analysis was performed on all selected cases estrogen level and T-value data. Change in each group at different stages of the levels of estrogen and T values repeated measures analysis of variance. Estrogen levels of the different groups at same time point has no significant difference (P>0.05), but a significant difference (P<0.05) in T-value of the different groups at different time points. The same group after injury on1st day and3rd day postoperative levels of estrogen and T values has no significant difference (P>0.05). The same group on the14th day and the45th day postoperative levels of estrogen and T value compared to on the1st day after injury and the3rd day postoperative has a significant difference (P<0.05). The same group on the45th day postoperative levels of estrogen and T values compared to on the14th day postoperative was significant significance. Three groups of patients estrogen levels after injury and postoperative were significantly elevated, T value on the14th day after surgery also increased, P<0.001significant difference. All patients has an obvious correlation between estrogen levels and bone mineral density T-score, the correlation coefficient r=0.358, P=0.002. Conclusions The research indicates that estrogen level will rise when the organism is suffered from external trauma or major operation. The variation of female hormone plays an effect on bone mineral density which leads to the rising T value. With the decrease of estrogen levels, eventually leading to localized osteoporosis increase. If hip fracture in older men patients were given the right amount of estrogen, may help to delay the aggravation of osteoporosis.