Optimization Of CSFV And PRRSV Immunization Programs For Large-scale Pig Farms

CSF and PRRS, two major infectious diseases, are widely epidemic around the world and threat to the healthy development of the pig industry seriously. Pigs infected with CSFV or PRRSV have poor immunity. Meanwhile, the herd will be infected mix CSFV or PRRSV with other diseases and those diseases causes swine farm serious losses. In addition, the breeding environment and different vaccine can produce different immune effect, and the pig group of immuned CSF vaccine may make some disease immunity effects due to immune suppression.In this paper, a large-scale pig farm in Sichuan was used as the testing farm, the change of antibody levels of CSFV and PRRSV after vaccination by different immune programs were analyzed by methods of ELISA, and qualification analysis, to test a economic and possible immune programme for the test farm.The results show that, after immune to test swines by the attenuated CSFV vaccine, for multiparous sows, breeding boars and commercial pigs, compared with group A and C, it’s better of the immune effects than the test group B immunization program. For multiparous sows, the less of the number of immunization and less stress for pigs was satisfied in group B. For breeding boars, group B immune fewer and designed in the test period to maintain an effective rate of protection. For commercial pigs, after the last immunization3months, the antibodies pass rate group A and C was significantly lower than group B. And the antibody titer is low, the downward trend is obvious and faster. Therefore, if the test farm will use this vaccine, we suggest they use the group B.Also, with the attenuated PRRSV vaccine, for multiparous sows, breeding boars and commercial pigs, compared with group A and C, it’s better than the immune erects whan test group B. For multiparous sows, the immune effect of the group B is relatively better than group A and C. For breeding boars, the difference of immune effects in the three groups immunization programs is not very obvious, but the smaller dose, more appropriate times and satisfied immune effect were advantages in the group B. For commercial pigs, the group B immunization program were more reasonable and higher rate of protection. Taken together, if the test farm will use this vaccine, we suggest they use the group B.Thus, the trial for the test farm can be refered to the immunization program for both CSF and PRRS vaccine-preventable diseases.