Fluorescent Chemosensors For Detecting Metal Ions Based On DPA

Via transforming the molecular recognition information into the optical signal easy to monitor, fluorescent chemosensor has become the preferred method for detecting a complex system cation, based on its specific selective, high sensitivity, convenient and efficient nature. How to design and synthesize a sensor with the specified function had been studied extensively. DPA is a common recognition of the Group. Its three nitrogen atoms containing nonbonding electron may be partially or simultaneously involved with the complex. Based on this, it is also got a wide range of attention. We designed and synthesized two kinds fluorescent chemosensor based on DPA. Their optical properties and the ability to identify the ions were studied by a variety of methods, such as UV-vis, fluorescence and IR. The recognition mechanism was also studied.1. Based on photoinduced electron transfer (PET) mechanism, we designed and synthesized a chemosensor named DQ, through using quinoline as reporter matrix and DPA as recognition group. Its optical properties and the capability to identify the ions were studied by UV-vis and fluorescence methods. Usually, zinc ion was similar to cadmium ion, so they were interfered with each other. We distinguished the two ions in the fluorescence intensity and emission wavelength by two different recognition mechanism. The mechanism was caused by the amide tautomerism. We proved it was true by NMR and infrared.2. We designed and synthesized a chemosensor named RB2based on rhodamine’s special optical properties, through using rhodamine as reporter matrix and DPA as recognition group. The optical spectra showed that the sensor was good at combining with the Fe3+ions. Even the complex in a system full of amount of other ions was not affected. Furthermore, we believe that when we only change the reporter matrix without changing the recognition group and relay group, the different recognition ability was derived from the spatial configuration of the impact.3. We detect the fluorescence reponse to defferent pH and the cell toxicity by MTT method. Then we consider the two chemosensors could be used in complex system. Moreover, the two sensors can effectively distinguish different ions in cell, respectively.