Lcq Questionnaire Evaluation Clinical Research Of Subacute And Chronic Cough

The paper is composed of literature Review and clinical research.Literature ReviewTCM literature review:Give an account of several generations of TCM scientist on the etiology and pathogenesis. syndrome type, therapeutic principle of chronic cough. Also summarizes some current pharmacology research about single herb and compound preparation on chronic cough treatment.Western medicine literature review:Summarizes the epidemiology, etiology, pathogenesis of subacute and chronic cough, and the common disease which causes chronic cough, in the pathogenesis of the disease, the main clinical symptoms, diagnostic criteria, treatment principles. But also provides an overview of the main cough on quality of life evaluation scale and cough efficacy evaluation method.Clinical researchObjective To find out the influence of subacute cough and chronic cough on patients’ quality of life by the LCQ questionnaire, and evaluate the correlation of two efficacy evaluation methods of Leicester cough questionnaire (LCQ questionnaire) and cough symptom score. Methods Patients met the inclusion criteria for the diagnosis of subacute, chronic cough patients, that treated with TCM therapy and(or) in combination therapy, treatment for14days. Before and after treatment, respectively LCQ questionnaires and cough symptom score evaluation; Analyzing the common causes and characteristics of subacute and chronic cough; Researching the affect of subacute and chronic cough on the quality of life for patients. Through T-test, rank sum test and Kappa statistics, analyzing the correlation of two evaluation methods. Results124cases was taken into the research, but4cases was lost. Finally, there were120cases that have statistical significance. Among the samples, cough after infection (CP1)(35.8%) is the main cause, followed by cough variant asthma (CVA)(25.8%),both accounted for more than1/2of the subjects; The impact of subacute, chronic cough on the patients’ life quality with varying degrees, especially in sleep disorder、 Influence the daily work and communication and so on; Through treatment, patients performed the LCQ questionnaire, and there is significant improvement on the three major regions of psychological, physical, social (p<0.05); There is a well consistency between LCQ questionnaire and cough symptom score on evaluate the treatment effect of subacute, chronic cough.(P>0.05,kappa=0.534). Conclusions The main cause of chronic cough is cough variant asthma, cough after infection, chronic bronchitis, gastro esophageal reflux disease, upper airway cough syndrome, eosinophilic bronchitis; The common TCM syndromes chronic cough is Phlegm retention in the lung, Cold pack fire, Wind-heat Fan fei. Irascibility Fan fei; Subacute cough and chronic cough significantly affect the quality of patients’life, the main effects is affecting the life and work, affecting the daily exchange, affecting sleeping, feeling embarrassed in public places; LCQ questionnaire and TCM symptom score on evaluate the treatment effect of subacute. chronic cough has a well consistency.