Kidney Invigorate The Party And The Related Research Of The Open Square In Patients With Ankylosing Spondylitis

Purpose： ThisstudyobservedthekidneyHuoxuesideinankylosingspondylitis(AS) in patients with TNF-α, TGF-β1, IL-18, IFN-γ effect, to investigateTNF-α, TGF-β1, IL-18, IFN-γ in the pathogenesis of ankylosing spondylitisthe role of BHD Treatment of ankylosing spondylitis some possible mechanisms,which reveals the compatibility of law and prescribing their exquisite location,a Chinese medicine treatment of ankylosing spondylitis in the area of the fieldof molecular biology to provide a theoretical and experimental basis.Material and method：Thetestsubjectswereall120patientswithorthopedichospital in Shenyang City, hospitalized patients were randomly divided into4groups, namely Western medicine group, kidney side group, blood group and sideBHD group,30cases in each group.After the end of each drug, byimmunohistochemistry (SABC) method to detect the group IL-18, IFN-γ, TNF-α,TGF-β1protein expression products.Results：1.BHF group TNF-α expression was significantly lower than before treatment,significant difference before and after (P <0.05).2.BHD group TGF-β1expression was significantly higher than before treatment,two group difference was significant (P <0.05).3.BHD group IL-18, IFN-γ expression was significantly lower than beforetreatment, two groups were significantly different (P <0.05).Conclusion：1.IL-18, IFN-γ, TNF-α, TGF-β1and other inflammatory meson directly involvedin the pathogenesis of ankylosing spondylitis, AS patients with IL-18, IFN-γ,TNF-α, TGF-The abnormal expression of β1may be new to the pathogenesis ofAS.2.the experimental study of the kidney were square, square and Invigorating Blood Fang in AS patients with serum IL-18, IFN-γ, TNF-α, TGF-β1content, suggestingthat BHD, has the reduced IL-18, IFN-γ, TNF-α expression levels, increasedlevels of TGF-β1expression in the role specified to protect bone tissue, thepurpose of treatment of ankylosing spondylitis.