Discharge Turbid Blood Middle Party Treatment Of Renal Fibrosis Of Patients With Chronic Renal Failure Clinical Studies

Objective:To observe the turbidity relief to remove early or middle side treatment of chronic renal failure and its clinical effect of endogenous creatinine clearance (Ccr), creatinine (Scr), GSH inhibition change C(Cys-C), serum transformation growth factor-β1(TGF-β1), Ⅳ collagen type (ColIV) influence.Method:Choose this topic research standard of patients with chronic renal failure of64cases were randomly divided into the treatment group and control group in two groups, and the32cases. Two groups of patients to western medicine treatment are based, on the treatment based on patients with treatment group and discharge to remove turbidity side treatment, the control group symptomatic treatment. Observe the clinical curative effect of two groups of patients before and after treatment and endogenous creatinine clearance (Ccr), creatinine (Scr), GSH inhibition change C (Cys-C), serum transformation growth factor-β1(TGF-β1),Ⅳ collagen type (ColIV) change.Results:The two groups before treatment Ccr, Scr, Cys-C, TGF-β1, Col Ⅳ comparison (P>0.05), are comparable. After the treatment of traditional Chinese medicine clinical symptoms control rate of65%, the treatment group was85%; After the treatment group, Scr, Ccr Cys-C, TGF-β1, ColⅣ and control group after treatment with significant difference (P<0.05).Conclusion:Relief to remove early or middle of turbidity party kidney failure patients have better clinical curative effect, the improvement of kidney function mechanism and TGFβ-may suppress1, Col IV, Cys-C expression, thus inhibiting renal fibrosis relevant.