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Patients With Anterior Wall Myocardial Infarction Complicating Aneurysm Bnp And Hs - Crp After Pci Treatment Of Prediction Value And The Analysis Of Tcm Syndrome Types

Posted on:2013-12-17Degree:MasterType:Thesis
Country:ChinaCandidate:X H WangFull Text:PDF
GTID:2244330395479090Subject:Integrative Medicine
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Purpose:To evaluate the effect of PCI in the patients who get the anteriormyocardial infarction with ventricular aneurysm and the change ofN-terminal B-type natriuretic peptide (NT-proBNP), serum high-sensitivityC-reactive protein (hs-CRP) in perioperative period of PCI, and whetherthese factors could be early predictors of ventricular aneurysm.Finallyanalysis of the aneurysm patients in perioperative period of PCI TCMsyndrome type changes that can be used, conditioning, the Integrativeinhibition of ventricular remodeling.Material and method:43cases with anterior myocardial infarction who underwent PCI,including31males and12females, average aged58.3±12.1(55-69)years old; previous PCI, severe infection, tumors, rheumatic diseases,infectious disease, liver and renal insufficiency excluded. Based on leftventricular angiography, the patients were divided into ventricular aneurysm group and control group. All patients were got the blood serumsample of hs-CRP、NT-proBNP before PCI, and hs-CRP12-16h orserum NT-proBNP after48h. Ultrasonic cardiogram, ECG,serum NT–proBNP and hs–CRP were followed up in one month. First of all,according to EF and left ventricular internal diameter of1month aftersurgery in the ventricular aneurysm group,25people confirmed thesignificance of the PCI in ventricular aneurysm in patients. Followed bybetween ventricular aneurysm groups and control groups comparehs-CRP preoperative and postoperative12-16h, NT-proBNP preoperativepostoperative48h and after one month, making a comparison confirmedthat hs-CRP and NT-proBNP for ventricular aneurysm in patientsundergoing PCI of the predictive value. Application of SPSS17.0statistical software measurement data to mean±standard deviation(X±S), the mean between the groups were compared using t-test; countdata using the X2test, the difference was statistically significant (P <0.05).Results:1:Compared pre-PCI and48h after PCI in Ventricular aneurysm group, the LVEF(Left ventricular eject fraction, LVEF;0.547±0.101vs0.565±0.092P=0.513>0.05) and LVEDD (left ventricular diastolicdiameter, LVEDD;52.52±6.838vs50.84±5.720P=0.351>0.05) werenot significant difference.But there were significant difference of LVEF(0.547±0.101vs0.602±0.072P=0.031<0.05) and LVEDD (52.52±6.838vs47.16±4.119P=0.002<0.05) between pre-PCI and one month after PCI.2:Compared to Control group, serum hs-CRP preoperative,postoperative12-16h in the ventricular aneurysm group were significantincrease(7.941±10.111vs2.817±3.696,7.534±10.654vs2.143±2.748Pvalue were0.047and0.043). Serum NT-proBNP pre-PCI,48h and amonth after PCI in the ventricular aneurysm group were significantdifference(1749.445±1965.263vs714.776±835.15,2136.828±2835.75vs502.36±495.43,1195.22±1515.53vs490.88±565.11P value=0.042,0.02,0.041).3: Preoperative TCM, more than43cases of patients with anteriormyocardial infarction and blood deficiency, blood stasis-based PCI postoperative Qi Deficiency, blood stasis, heart yang lack of permit, Qiblood stasis and heat toxin attacks the card, liver and spleen do not tunethe card.Conclusion:1Our study show that LAD PCI can improved the LVEF and LVEDD ofLeft ventricular aneurysm patients in one month.2Serum hs-CRP and NT-proBNP have predictive value for ventricularaneurysm patients around the PCI period.343cases of patients before surgery, TCM Integrative conditioning thepatients, which will help patients with early rehabilitation.
Keywords/Search Tags:Ventricular aneurysm, BNP, hs-CRP, PCI, TCM dialectic treatise
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