In 2006-2011 Of Acute Inpatient Main Flora Distribution And Drug Resistance Situation Investigation

ObjectiveTo study the distribution and drug resistance of the main pathogens in our burn department from2006to2011, so as to provide the scientific basis for antimicrobial therapy.MethodsTo retrospectively analysis the bacterial culture and drug sensitive results of our burn department in recent5years. The bacterial determination and drug resistance test were performed by WalkAway96Automated Microbiology System for Identification; the data analysis used WHONET5.6software.Results308strains of bacteria were isolated from113inpatients. The common pathogens successively were Pseudomonas aeruginosa, Staphylococcus aureus, Acinetobacter baumannii, Xanthomonas maltophilia, Enterobacter cloacae and Klebesiella pneumonia, account for23.05%,21.43%,11.04%,4.87%,4.87%and4.22%respectively. Among the Staphylococcus aureus, the detection rate of the meticillin resistance S.aureus (MRSA) was90.91%; these isolates showed low resistance rate to chloromycetin trimethoprim-sulfamethoxazole and tetracycline, and there was no isolate resistance to glycopeptide antibiotics. The Pseudomonas aeruginosa and Xanthomonas maltophilia kept high sensitive rate of carbopenems and low sensitive rate of Piperacillin tazobactam and Cefopcrazone Sulbactam. Enterobacter cloacae and Klebesiella pneumonia showed high sensitive rate to imipenem (60%-80%), especially to Meropenem (100.00%) and the detection rate of the extended-spectrum β-lactamases (ESBLs) of them was more than1/2; Klebesiella pneumonia kept high sensitive rate to Piperacillin tazobactam (66.67%), while Enterobacter cloacae kept high sensitive rate to Romilxacin (90%).ConclusionBe with very serious resistance status, the burn department should enhance the test rate of specimen, so as to provide scientific basis for reasonably choosing antibiotics, in the end, to reduce the occurrence and prevalence of drug resistance bacterium.