| Objective: clinical characteristics and treatment methods of Chinese Medicine Hospital Ⅲ, Ⅳ of knot, and cancer patients, retrospective study and summarize;2, according to the clinical methods of treatment in advanced colorectal cancer patients divided into traditional Chinese medicine treatment Integrative treatment of two queues, contrast differences were observed in symptoms, quality of life and survival, to find a new clinical basis for Chinese medicine to participate in the comprehensive treatment of advanced colorectal cancer.Methods:A retrospective, screening contrast to clinical observation after the grouping. A total of76cases the clinical statistics of cases, according to the methods of treatment in our hospital is divided into traditional Chinese medicine treatment group and the Chinese and western medicine group, statistics, used in medical treatment more than3months in patients with the symptom score before and after treatment, KPS score and survival period than analysis.Results:76cases in the general condition of patients, male49cases,27females, mean age63.11±13.58years old, the main disease in the colon, accounting for51.3%; accounted for67.10%of lymph node metastasis, remote metastases the majority of liver and lung metastasis are above30%; Ⅲ of accounting for28.95%of Ⅳ accounted for71.05%, the majority of surgery and colonoscopy pathological diagnosis of adenocarcinoma, accounting for97.37%. Previous gastrointestinal history accounted for22.37percent,5.26percent of the family history of cancer, comorbidity, mostly hypertension, diabetes and coronary heart disease, respectively,23.68%,27.63%and10.53%.76cases of patients with Karnofsky score was75.53±11.82, symptom score of11.72±4.18, a negative correlation between the two. The most common symptoms of anorexia, abdominal pain, fatigue, pain, bloating, poor sleep, loose stools, constipation, etc., the most common syndrome of qi deficiency. Integrative Medicine in74patients accounted for47.37%, and accounted for52.63percent of Chinese medicine treatment. The comparative analysis of the two groups were30cases and found that the poor efficacy of traditional Chinese medicine treatment group to improve the high symptom score (15points). Two groups of various symptoms to improve the terms of the distribution are more balanced. But to improve the symptoms of anorexia and intestinal dysfunction, more general, also confirmed the poor gastrointestinal function in patients with advanced colorectal cancer treatment should be strengthened in this regard. Quality of life, showing the two groups before and after treatment KPS score statistics are basically in a stable, two groups no significant difference (P>0.05). In terms of survival of the combination of Chinese and Western treatment group showing a slightly better than the trend of Chinese medicine treatment group in the1-,2-and3-year survival rate, due to sample size is less, by log-rank test, P=0.331. no significant difference extended median survival of8.9months.Discussion:a Chinese medicine hospital late junction in patients with rectal cancer aging majority, colon than the rectum, consistent with the trend of world development; advanced colorectal rectal cancer qi deficiency, blood deficiency, three toxic stasis syndrome group more of their the improvement has become the main task of the Chinese medicine treatment in patients with advanced colorectal cancer;3, anorexia, and fatigue are the main symptoms of anorexia symptoms improve still further attention; Chinese medicine treatment of advanced colorectal cancer has a place, which multi-angle, multi-means of diagnosis and treatment is the most important methods of treatment, followed by also focus on nursing the spleen; Chinese and Western combined treatment group, median survival time extended by8.9months compared with traditional Chinese medicine treatment group, with the obvious meaning, but in1,2and3of the overall survival rate is greater than the TCM treatment group, need to do further large sample... |
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