Small And Medium-sized Follicle Ovulation Infertility Tcm Syndrome Distribution Regularity Of Research

BackgroundIn recent years, the increasing trend of female infertility incidence of ovulatory dysfunction is one of the reasons causing the infertility of women of childbearing age, accounting for25%to30%of the infertile patients. Small follicles ovulation attribution is an ovulation disorder, its incidence into the occult, infertility patients found that small follicles in the process of monitoring follicular ovulation, it accounted for27%of the non-pregnant women, accounting for unexplained infertility women68.7%. Currently, the pathogenesis of small follicles ovulation inconclusive, the researchers will locate on the in Follicles steroid hormones, peptide hormones and related receptors and ovarian local micro-regulator. Clinically, the small follicles of ovulatory infertility has clear diagnostic criteria. Ovulation induction drugs and assisted reproductive technology-based treatment, but because the drugs are expensive, the technology is not yet universal, more complications, its application is limited.Chinese medicine has had a long discourse on infertility, but not systematically differentiate ovulatory dysfunction (small follicles ovulation) infertility, according to the description of its main symptoms, can be scattered "no child,""died out ","amenorrhea","irregular menstruation" chapters. Chinese medicine believes that infertility etiology and pathogenesis of kidney, liver depression, phlegm, blood stasis and kidney deficiency as a core. In the treatment will be the combination of differentiation with disease and create artificial cycle of traditional Chinese medicine therapies to reduce the complications and adverse reactions of the simple application of western medicine, has made a good effect. But the disease is the lack of a unified TCM syndrome Hou diagnostic criteria, which restricted after the objectivity of the evaluation of traditional Chinese medicines and normative, scientific and objective mathematical statistics to introduce the Hou study.PurposeThis study investigated the ovulatory dysfunction (small follicles ovulation) Infertility common clinical manifestation and distribution of syndrome law, so as to further understanding of the etiology and pathogenesis of the disease and related factors, TCM syndrome Hou standardized, objective, in order to can more accurately guide clinical and carry forward the Chinese medicine essence of brilliance.MethodThis research adopts investigation, epidemiological investigation, pre-survey, and consulting experts in the method, prepared to contain the basic situation, the four diagnostic information, monitoring of follicle situation questionnaire, and then create the database with the following statistical methods:descriptive analysis factor analysis, chi-square test of TCM Hou of small follicles of ovulatory infertility as well as distribution of the initial exploration and study.Result1. This study collected306cases of patients met the inclusion criteria, combined with the pre-survey results, summed up a total of51clinical symptoms and23of the tongue and pulse performance. By factor analysis, reached a total of nine syndromes: deficiency syndrome (45cases), kidney yang deficiency blood stasis (44cases), kidney yin deficiency syndrome (30cases), kidney-yin deficiency of the hepatic depression syndrome (34cases), liver and kidney syndrome (33cases), blood stasis (31cases), liver stagnation and spleen deficiency syndrome (21cases), deficiency of the hepatic depression syndrome (35cases), spleen deficiency syndrome (33cases). In order, as follows:the relevant certificate type of kidney> liver stagnation syndrome type> Blood Stasis Syndrome Type> Spleen dampness syndrome type. Yang (Qi) virtual card type> yin deficiency of the relevant certificate type. The above data suggest that:kidney, liver depression accounted for the main aspects, spleen, phlegm, blood stasis card is a secondary aspect.2. Small follicles of ovulatory infertility, mostly concentrated in the26to35years old,65.36%of the total number,31to35-year-old accounted for the largest proportion of33.33%.This situation is related to the following factors:age of marriage, treatment, and living environment, personal economic conditions. Age and infertility in this survey and can not be simply based on the statistical results to determine. Educational level is more concentrated in the university, the majority of mental worker, may be associated with liver depression factor. The clinical symptoms:premenstrual breast tenderness, irritability, flank pain, mouth and throat pain.3.The age distribution of the disease related to age,20to25years of age to the highest proportion of liver and kidney card,26to30years of age to the highest proportion of kidney yang deficiency and Chief stasis syndrome,31to35-year-old Yang and blood stasis, spleenand kidney yang-based,36to40-year-old kidney liver depression and blood stasis.4. Hou distribution related to intrauterine operations and permit. Intrauterine operating patients with a history of and kidney yang deficiency Chief stasis proportion (17.6%) the highest, no operating history of the uterine cavity in patients with Kidney Yang Deficiency Chief liver depression and proportion (18.5%). Primary infertility patients with spleen deficiency (18%) and Kidney Yang Deficiency and Chief stasis (15.8%) the main and secondary infertility (17.6%) to blood stasis, kidney yang deficiency and Chief stasis (14.1%) and kidney yin deficiency and Chief liver depression (14.1%) dominated. ConclusionKidney deficiency is the main pathogenesis of anovulation infertility(Small follicles ovulation), any reason leading to kidney-menstruation-Chong and Ren-the uterus of reproductive axis function disorders will affect the development and maturation of the follicles. Those who can damage the kidney, leading to kidney factors are small follicles of ovulatory infertility factors related, the other chief certificate to each other and kidney. Age, abortion history, abortion way to permit the distribution of Hou. Treatment should be invigorating kidney deficiency and regulating the main differentiation with disease combining with the permit rule.