Kidney Tonify Deficiency Blood Fights Method For The Treatment Of Chronic Glomerulonephritis 60 Cases Of Clinical Research Summary

Chronic glomerulonephritis, referred to as chronic nephritis, is a kind of common disease in internal medicine, can occur in different age, especially in the young and middle-aged. It has the highest incidence in kidney disease. It’s a slowly continuous development, can have different degrees of renal dysfunction, and chronic renal failure. At present domestic and foreign to this sickness treatment means are scarce, and Chinese medicine in the treatment of chronic nephritis proteinuria, improvement of clinical symptoms, delaying the decline of renal function and other aspects has a certain effect, so the research on TCM treatment of chronic nephritis, has very important significance.This paper is divided into Chinese literature review and clinical research in two parts. Chinese literature review mainly discusses the modern Chinese for chronic glomerular nephritis by TCM name, etiology and pathogenesis, syndrome differentiation and modern clinical research. The research is a part of "11th five-year plan" national science and technology support plan-" The treat safety and effecticness cohort study of LvRenhe professor’s treatment for chronic kidney disease based on syndrome differentiation like three pattern types and four syndrome types ".This study was based on the clinical experience of Professor Lv Renhe for many years in the treatment of chronic nephritis, and used the method of Yishen Buxu Huayu Sanjie (Basic components:Astragalus, Chinese yam, broil tortoise plastron, Ligustrum lucidum, epimedium, Rosa, Gorgon fruit, radix salviae miltiorrhizae, Radix cyathulae, Euonymus alatus) to treat60cases of chronic nephritis, and we set up the non-exposed group in60patients, two groups were treated with same Western Medicine (general treatment and symptomatic treatment), The treatment was lasting for6months, observed in patients with glomerular filtration rate, quantitate of24-hour urine protein, urine protein, urine red blood cell number, symptom scores and other improvements.After the treatment for2months and6months,the results are:1. Exposed group of glomerular filtration rate are improved obviously after treatment, and the differences were statistically significant (P<0.001), while the non-exposed group show a downward trend, but the difference was not statistically significant (P>0.05).2. Exposured group in the routine urine proteinuria efficacy analysis of exposed group total effective rate was obviously higher than that of the non-exposed group, the difference was statistically significant (P<.0001).3.Exposured group of TCM syndrome integral decline, the differences were statistically significant (P<.0001).4. Exposured group24-hour of urine protein quantitative declined, instead of the non-exposed group were slightly increased, but the differences of two groups were not statistically significant (P>0.05).5The exposed and non-exposed groups in the course of treatment of urinary red blood cells were relatively before slightly downward trend, but the difference was not statistically significant (P>0.05).6.After2months treatment, the exposed group,60cases were studied, clinical control3cases, marked effective9cases, effective28cases, nvalid20cases, the total efficiency was66.7%;The non-exposed group,60cases were studied, clinical control0cases, marked effective1case, effective11cases, nvalid in48cases, the total effective rate was20%.After6months treatment, clinical control8cases, marked effective14cases, effective in19cases, nvalid19cases, the total efficiency was68.3%; non-exposed group, clinical control in2cases, marked effective0case, effective10cases, nvalid48cases, the total effective rate was20%.Conclusion:the method of Yishen Buxu Huayu Sanjie can significantly improve the clinical symptoms of patients with chronic glomerulonephritis, improve patients’quality of life; reduce urinary protein, elevate glomerular filtration rate, effectively improve renal function; It has significant efficacy, clinical feasible, good safety, and can cut off and delay chronic nephritis progression.It has very import significance.