| Suan-Zao-Ren Decoction is come from "Jin Kui Yao Lue", which is composed of Suan Zao Ren, Chuanxiong, Zhimu, Fuling, Gancao. Reinforcing the liver blood, healthy the spirit of heart, clearing heat and relieving fidgetness, Mainly attending liver blood deficiency, virtual heat caused by interference in the "virtual fatigue virtual vexed shall not sleep".ObjectiveThis article through to the ancient and modern literature analysis of Suan-Zao-Ren Decoction, this paper summarizes and analyzes the characteristics of its clinical application, the type of disease, choice of basis, such as drug components, trying to find its clinical application rules and function effect to material foundation, to look forward to provide certain evidence for clinical application.Contents and MethodsClinical summarized the clinical application of disease types and application and their application in the spirit system, cardiovascular system disease illness, skin disease, female and male diseases related diseases and other therapy combined with the application and the sum of the application.Mechanism research reviewed the Suan-Zao-Ren Decoction in the treatment of mental system disease, especially insomnia and anxiety related diseases such as card mechanism of action and link, through the related research, reveals the effect to link and targets. Prescription components, for the various means of chemical components of pharmacology study summarized, reveals the effect to the material basis of chemical composition and drug interactions.Through the use statistical methods, for the clinical treatment of disease types and treatment drug use frequency are analyzed and summarized.Results1. The document Suan-Zao-Ren Decoction mainly concentrated in the application of clinical cases observation and resistance to anxiety, calm and related mechanism research, also had the part of literature research about components, but compared with the current clinical reports, this section is relatively rare.2. Suan-Zao-Ren Decoction besides mainly used in treatment mental system common insomnia, depression syndrome, anxiety disorders of the card give priority to card, still can treat the nervous system disorders, improve women’s menopause syndrome and the male reproductive system related diseases, skin disease also used for certain applications. Its clinical application scope has been greatly expanded and is not confined to tranquilize mind treatment.3. Through the analysis found that, now clinical application Suan-Zao-Ren Decoction treatment disease, in addition to use application Suan-Zao-Ren Decoction, most clinical are combined with other herbs to add and subtract application, and is not limited to add and subtract simple formulae, combined with acupuncture and moxibustion, massage, and other therapy many applications.4. Suan-Zao-Ren Decoction mechanism research, mainly focus on its resistance mechanism of anxiety and calm, results suggest that the antioxidant anxiety and calm and inhibition mechanism of central nervous system very excited, brain tissue of endorphins content rise, at the same time, relevant, and increasing brain tissues in size to improve by GABAA GABAA can function relevant.5. From drug use frequency statistics result, Suan-Zao-Ren Decoction four square gout drug is located in the top four, and other drug astragalus focused on fill gas, big jujube focused on blood, are also in the square of Suan-Zao-Ren Decoction conception are identical with each other. Visible in clinical application process, Suan-Zao-Ren Decoction for different clinical application still prevention and control of diseases subject drug use. It may also conforms to the cube of Suan-Zao-Ren Decoction intended.Conclusions1. The ancient documents from the sorting of results can be seen, and now the use of Suan-Zao-Ren Decoction basically based on two ideas to launch, one is strictly according to the synopsis of Jin-Kui-Yao-Lue for clinical use; Two is based on Suan-Zao-Ren Decoction and the pathogenesis and formula law party, trying to expand the application range of the or add and subtract, or in combination with other different formula and treatment in order to adapt to the different disease performance.2. In the formula, and in accordance with the five elements of traditional Chinese medicine in raw physiological relations, according to five line born g relationship, liver for the mother of heart, mother can make false, blood deficiency of liver and heart a displaced insomnia, mother of disease and the reason the son, so for decreasing the children to enforce the mother.3. Use frequency statistics from herbs and clinical application and can be seen, the square of Suan-Zao-Ren Decoction compatibility structure is relatively stable, in the original party on the basis of overall use, add flavor or in combination with other therapy is to use the basic thought of Suan-Zao-Ren Decoction, clinical curative effect is to ensure that one of the important factors. 4. The results of the study show that modern mechanism, Suan-Zao-Ren Decoction mainly embodies the calm and resistance to the role of anxiety, so the main focus on clinical spirit system the treatment of diseases, such as insomnia, anxiety, depression and anxiety and his partners composed effect related disease types.5. The chemical composition, the results indicate Suan-Zao-Ren Decoction in the treatment of function, its main the gentleman medicine Suan-Zao-Ren chemical composition saponins and flavonoids related, at the same time, and the other party between drug chemical composition of the synergy between each other but also to play its curative effect. |
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