The Stones Ercp Nipple Incision Postoperative Pancreatitis Factor Analysis

Background:More than50years have passed since ERCP have been wildly used in clinical practice. More and more study about the complication has been done and now people give more attention to the precaution. According to the previous study, patients-related factors and the procedure-related factors both influence the incidence of PEP. Objective:The goal of this study is to evaluate the influence factors of post-ERCP pancreatitis over398patients in our center.Methods:We collected398cases in which patients received ERCP because of oledocholithiasis from2003to2011and327cases was chosen according to the inclusion and exclusion criteria. To do the data analysis, software SPSS17.0Stat. was used. The327cases was divided into two groups:PEP group and non-PEP group and the information that we collected was divided into two parts:the basic data and the ERCP-related data. We chose the X2test and t test to do the univariate analysis and the logistic regression to do the multiplicity. The definition of the complication of ERCP was made according to the Consensus of the de Complications of ERCP that was mentioned in 《ERCP》，Chapter6.The expansion degree of bile duct was made according to clinical experiences of our center which is normal(d≤1.0cm), mild(1cm<d≤1.5cm), moderate(1.5cm<d≤2cm) and severe(2cm<d).Rrsults:1、The statistical analysis was performed on327patients, on whom the PEP was occurred, of the398patients.23(7.03%) patients who had the complications all suffered mild pancreatitis, and are all cured by conservative treatments and there was no death.2. All the cases was divided into two groups, the PEP group and the non-PEP group. The result of univariate analysis shows that the occurance of PEP was related with the medical history of cholecystolithiasis、TBIL、DBIL、ALT、AST、GGT、TG and the standard of oledochectasia.3、Multiplicity shows that only the medical history of cholecystolithiasis and the standard of oledochectasia are related.4.6of the patients who had PEP have normal bile duct and the other17patients have mild-expansive bile duct. None of the patients who have moderate or severe expansive bile duct suffer PEP.Conclusion:1、The patient who has the medical history of cholecystolithiasis and a more normal choledoch has the lower risk of PEP.2、 Other risk factors such as sex、age、and operating related factors shows no statistical difference in our study.