The Axial Coordination Naphthalene Phthalocyanine Synthesis And Optical Dynamic Performance Research

As an ideal and non-invasive tumor treatment method, photodynamic therapy hasgained more and more attention. The current research of photosensitizer has mainlyfocused on phthalocyanine and naphthalocyanine complexes with planar structure, butnot much has been done about those with axial ligands. Therefore, this papersynthesized three novel silicon naphthalocyanine complexes with axial ligands of（NO₂）₄NcSiCl₂,（NO₂）₄NcSi（CH₃O）₂and （NO₂）₄NcSi（C₂H₅O）₂, and their structureswere characterized via infrared spectroscopy, UV-Vis spectroscopy and elementalanalysis.In this paper, the UV-Vis spectra of the three complexes in different solvents wereinvestigated, and the effect of different axial ligands and different solvents on them werediscussed. The results showed that with the enhancement of the pushing electroncapacity of the axial ligands, the maximum absorption wavelength of thenaphthalocyanine compounds redshifted.Photostability and singlet oxygen yield of the naphthalocyanine compounds werealso studied. The results indicated that （NO2）4NcSi（CH3O）2has better photostability anda larger yield of singlet oxygen as an ideal photosensitizer for further study.In addition, the synthetic conditions of4-nitro-α,α,α’,α’-tetrabromo-o-xylene and6-nitro-2,3-dicyanonaphthalene were studied, and the optimal conditions were obtained,which increased the production rate and reduced the cost.