The Application Of Ultrasound-guided Automatic Biopsy Technology Clinical Study In The Diagnosis Of Oral And Maxillofacial Neck Mass

Objective: Oral and Maxillofacial neck mass is a common representationof many diseases of the oral and maxillofacial surgery, can be grown in anyarea of the oral and maxillofacial and neck.Oral and Maxillofacial neck massetiology is complex and difficult to diagnose, the different nature of mass istreated in different ways.It is directly related to the treatment and prognosis ofthe disease that timely clear oral and maxillofacial neck to unknown reasonsmasses pathological diagnosis.Currently，conventional diagnostic for oral andmaxillofacial neck mass still rely on traditional histopathological diagnosis,with its major diagnostic criteria being histological changes.Recent years,ultrasound-guided automatic biopsy technology become more sophisticated,and have been widely used in the thoracic cavity, abdominal, pelvic, andsuperficial organ lesions biopsy.Currently, ultrasound-guided automatic biopsytechnology has been considered the best way to get clear histopathologicaldiagnosis in non-surgical conditions, but fewer diagnostic applications of thistechnology in oral and maxillofacial and neck lesions.This paper will explorethe reliability of that ultrasound-guided automatic biopsy technology apply inoral and maxillofacial neck to unknown reasons masses in patients with biopsydiagnosis，summarize such a clinical diagnostic value take seized oral andmaxillofacial neck mass, evaluate its feasibility as conventional biopsymethods,and provides for the treatment of patients based on clinical diagnosis.Methods: Experimental group selected from June2011to September2012, the Fourth Hospital of Hebei Medical University, Oral and MaxillofacialSurgery,89cases of hospitalized patients.89cases were oral and maxillofacialneck mass patients,the minimum diameter of mass is1.5cm, the maximumdiameter is13cm. All patients were perfecting a routine examination, exclusion of anesthesia and surgery taboo preoperative conversation, informed consentsigned puncture surgery automatically under its line of ultrasound-guidedautomatic biopsy. To further confirm the ultrasound-guided automatic biopsytechnology on clinical diagnostic value of oral and maxillofacial neck mass,the experimental set up two control group. Control group1: The sameperiod,46patients intraoperative frozen section biopsy diagnosis results wascollected. Control group2: the same period,the results of qualitative diagnosisof76patients by fine needle aspiration cytology was collected. The diagnosticresults of the three methods of biopsy are the postoperative the paraffinsections pathological diagnosis results as the gold standard, diagnostic resultsregard the benign lesions of mass as a negative standard, Experimental resultsusing the SPSSl3.0statistical software diagnostic test and the chi-square testanalysis, taking P <0.05was considered statistically significant, through theanalysis of experimental results testing ultrasound-guided automatic biopsyand Postoperative paraffin sections histological types consistentrate,ultrasound-guided automatic biopsy, fine needle aspiration cytology, rapidintraoperative frozen biopsy whether there are differences in the diagnosticsensitivity, specificity, accuracy, whether statistically significant wasstatistically significant.Results:89patients by ultrasound-guided automatic biopsy technologytotally drawn204-pin,196-pin suit for histopathological diagnosis,drawnsuccess rate is96.1%(196/204). According to the pathological diagnosis ofthe exact degree of diagnostic pathology profession recognized gradingstandards,86cases of ultrasound-guided puncture histopathological diagnosisresults in line with the cases of0or1, The results showed96.6%(86/89) ofcases by ultrasound-guided automatic biopsy can get a clear diagnosis. Exactlyultrasound-guided puncture histological biopsy results of pathologicaldiagnosis and postoperative specimens paraffin sections pathologicaldiagnosis results in tissue histological types accounted for93.3%of the cases(83/89). Remove the three cases that is due to the drawn and other factors ledto can not confirm the diagnosis,86cases of ultrasound-guided automatic biopsy histopathologic diagnosis results with the results of the pathologicaldiagnosis of postoperative paraffin section diagnosis consistencyanalysis,Kappa value was0.930, with a high degree of consistency. diagnosticresults regard the benign lesions of mass as a negative standard,89cases oforal and maxillofacial neck mass in patients with ultrasound-guided automaticbiopsy pathology diagnostic accuracy, sensitivity and specificity were93.3%(83/89),89.8%(44/49),97.5%(39/40).46cases of intraoperative frozensection biopsy pathology diagnostic accuracy, sensitivity and specificity were78.3%(38/46),77.5%(18/24),90.9%(20/22).76cases of oral andmaxillofacial neck mass underwent fine needle aspiration cytology diagnosisaccuracy, sensitivity and specificity were75.0%(57/76),73.2%(30/41),77.1%(27/35). The experimental results using SPSS13.0software forstatistical analysis, The results showed that accuracy and specificity of theultrasound-guided automatic biopsy technology automatically superior to fineneedle aspiration cytology and intraoperative frozen section biopsy in thediagnosis of oral and maxillofacial neck mass, the difference was statisticallysignificant (P <0.05). It can not be considered that three biopsy methods isdifferent in the diagnostic sensitivity of oral and maxillofacial neck mass, P>0.05.Conclusion:1Ultrasound-guided automatic biopsy diagnosis accuracy is high in thediagnosis of oral and maxillofacial neck mass, highly consistent with thesurgery after paraffin sections pathological diagnosis results. Automaticultrasound-guided automatic biopsy operation is simple, inexpensive, shorteroperative time, little pain, drawn satisfactory result, no serious complications,it is a safe, quick, minimally invasive and effective means of biopsy, can beused as oralpreferred method of oral and maxillofacial neck masshistopathological examination.2Ultrasound-guided automatic biopsy technology compare withconventional fine needle aspiration cytology and rapid intraoperative frozenbiopsy, Ultrasound-guided automatic biopsy diagnostic accuracy and specificity is high, the difference was statistically significant.Experiments thatultrasound-guided automatic biopsy technology can be used in the clinicaldiagnosis of oral and maxillofacial neck mass as a conventional biopsymethods.