Clinical Observation About Dezocine Anesthesia And Fentanyl Anesthesia Combined Propofol Respectively For Painless Colonoscopy

Background and ObjectiveWith the social development and cognitive medicine gradually in-depth, people hope that modern technology or technology minimizes the impact of the disease. In the past, whether health care workers or patients think the only important is that the cure of the disease and some discomfort or pain is a necessary after surgery, unavoidable. However, with the advent of technology and expansion of painless, pain is largely to avoid or mitigate the torture. The reduction of pain not only helps the patient rehabilitation but also reduces damage to the patient’s psychological. The painless requirement are also increasing.Colonoscopy as an important method of diagnosis and treatment of diseases of the large intestine, has now spread to all levels of hospital. But such an inspection is invasive procedures to patients result in varying degrees of physical and mental suffering, some patients even refuse to inspection or review, resulting in delayed diagnosis. This seriously affects the doctor-patient relationship. Therefore, in recent years, painless test becomes the first choice of most doctors and patients. Currently anesthesia most commonly used intravenous anesthetics propofol because of its rapid metabolism. However, used alone propofol analgesic effect is not perfect, a larger dose would affect the hemodynamic stability, so we use fentanyl and propofol mostly. Fentanyl analgesic effect, but it has significant respiratory depression and affects ventilation, outpatient patients have a greater risk. Dezocine as a mixed opioid receptor agonist antagonist has analgesic effect, respiratory depression and drug dependence incidence rate is significantly lower than fentanyl.In this study, we clinical observates and contrasts dezocine united propofol for safety, effectiveness and superiority of painless colonoscopy.Objects and MethodsSelect80cases colonoscopy patients who is in ASA Ⅰ～Ⅱ in our hospital and then randomly divide into group A (dezocine combined with propofol group n=40) and group B (fentanyl combined with propofol group n=40). Observe two patients, mirror over the splenic flexure of colon, SpO2, HR, MAP, RR after operation, the time loss of consciousness (loss of eyelash reflex), body movement in operation, recovery time, VAS, and the total dosage of propofol. Finally follow up patients’ satisfi cation.We were recorded prior to administration of the two groups of patients, injection drug checks before the start of the colonoscopy began placed, colonoscopy splenic flexure of the colon, colonoscopy exit vitro MAP, SpO2, HR, RR. Recorded the two groups of patients with loss of consciousnesswhen (eyelash reflex), the total amount of intraoperative propofol, intraoperative body movement frequency, the number of respiratory depression in the surgery, after discontinuation of awake time after awakening or without nausea and vomiting, dizziness, discomfort, postoperative visual analog scale (VAS), the total amount of propofol, ask the patient satisfaction anesthesia Observance can wake up time (from the patient to be discharged).SPSS13.0version was used for statistical analysis. Measurement data was signified by mean±standard deviation(x±5).The comparison in groups was done with group t-test.Count data using χ2test. P<0.05was considered statistically significant difference.Results The two groups of patients with colonoscopy examination are successful. Patient and examining physician is satisfied with the anesthesia. Monitoring of vital signs between the two groups was no significant difference. Two groups of patients with loss of consciousness, propofol total amount of postoperative VAS score difference was not statistically significant. A group of the wake-up time and observation time compared with group B, the difference was statistically significant (P<0.05). The combination of B and A surgery was not statistically significant physical activity, apnea and postoperative nausea and vomiting, dizziness difference was not statistically significant (P<0.01).ConclusionsDezocine combined with propofol for the painless colonoscopy and treatment of analgesic effect and sedation is of exact effective, safe and adverse reactions. It is a kind of viable, effective painless colonoscopy anesthesia.