| Objective:To reveal the prevalence rate of Diabetes Mellitus (DM)/Impaired Glucose Regulation (IGR) in Tianzhu Tibetan autonomous county, Gansu province, in2012and analyze its risk factors.Methods:881residents aged between20and74were chosen from two villages and a community in a town (according to the local GDP rankings). All the residents had stayed in their places at least for five years. Using stratified cluster sampling method, the incidence of DM and IGR among those people was investigated from September2011to June2012. After the informed consents were signed by all the participants. their height, weight, waist circumference, hipircumference. Blood pressure, pulse, etc. were measured, the DM epidemiology survey forms were filled out at the same time. The Total Cholesterol (TC), Triglycerides (TG) and High Density Lipoprotein Cholesterol (HDL-c), Low Density Lipoprotein Cholesterol(LDL-c), Blood Uric Acid(UA),such as indicators, parallel75g glucose tolerance test (OGTT) were included according to the World Health Organization (WHO)1999diagnostic criteria for DM diagnosis. In data analysis, the SPSS17.0software was used.Results:The standardized DM prevalence rate of the county was4.98%, in the urban and rural areas, it was10.27%and3.28%respectively. The DM prevalence rate among Tibetans (7.11%) was higher than among Han people(4.51%), Men (5.26%) suffer the disease more easily than women (4.68%). IGR stand ardized incidence of the county was6.60%. in the urban and rural areas, it was8.67%and8.31%respectively. The IGR prevalence rate among Han people and Tibetans are7.51%and8.33%respectively. Among the42detected cases of DM,16was newly found accounting for38.1%of the total. The prevalence rate of DM increased with age. Their waist circumference, waist-hip ratio (WHR). body mass Index(BMI), high TG, high TC, high DLC-C, systolic pressure, diastolic blood pressure, fasting blood glucose(FBG), blood glucose tolerance test2hours (2HBG), sugar regulating normal (NGR), impaired glucose regulation (IGR) and DM order were found high. Compared with normal Glucose Tolerance group (NGT), people in the sugar regulation damaged group (IFG+IGT) and DM group have increasing ages, higher BMI, WHR, blood pressure, TC, TG and LDL-c. HDL-c value significantly decreased (P<0.01). Single factor logistic regression analysis showed that age, nationality, BMI, WHR, labor property, high salt diet and high fat diet, family history of hypertension, diabetes, high cholesterol, high blood triglycerides, high uric acid hematic disease, height14factors such as stress, infection of virus associated with DM and IGR disease significantly (P<0.005). Further USES the multifactor logistic regression analysis to alpha=0.05level reserves the variables in the regression model has a body mass index, waist-to-hip ratio, high fat, high salt diet, family history of diabetes, waist-to-hip ratio, high uric acid hematic disease, hyperlipidemia, hypertension and so on eight factors, its the OR values were6.431.3.640,4.519,10.960,7.276,2.772,5.627.Conclusion:In2012, the prevalence rate of diabetes among people aged20-74in Tianzhu Tibetan autonomous county was lower than the average level in China (9.7%), it increased with age. The prevalence rate among those who lived in towns (10.27%) was much higher than that of rural people. In rural areas, DM patients were far fewer than IGR ones. Different clinical and biochemical indices were found in various groups with sugar metabolic abnormalities. BMI, WHR, diet rich in salt and/or fat, records of diabetes in the families, high uric acid hematic disease, hyperlipidemia, hypertension identify the major risk factors behind the local DM. To reduce those risks, prevention and cure measures shoud be focused on people older than40, at the same time, close follow-up and regular detections are needed for families with records of diabetes and hypertension patients. |
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