Investigation On The Distribution Of The Traditional Chinese Medicine (TCM) Syndromes And Correlative Factors In The Type2Diabetes Mellitus Combined With Hypertension Disease

Objective: To investigate Traditional Chinese Medicine (TCM) Syndromes typeDistribution, common complications and related influencing factors of the type2diabetesmellitus combined with hypertension（DH）Methods: January2008to December2012,2466cases of type2diabetes mellitustreatment, xian yang City, Shaanxi Affiliateded hospital patient’s medical records wereretrospectively epidemiological investigated，survey content includes: general situation(age and gender), history of present illness, past history, allergies, family history(hypertension and diabetes), physical examination (Body mass index, Blood pressure andTCM four diagnosis), and auxiliary examinations (blood lipids, blood glucose, urineroutine, glycated hemoglobin and abdominal ultrasonography)，etc. hospitalized diabeticpatients were divided into two groups: the diabetic normotensive patients (DNP) group(1420cases) and the combined hypertention group (1046cases), or grouped by gender:male group and female group; and then each group were divided into two Parts: thediabetic normotensive group (1420cases) and the combined hypertention group.thedifferences of relevant factors,Traditional Chinese Medicine (TCM) Syndromes typeDistribution and common complications among the different groups were compared andanalyzed.the results obtained usingSPSS17.0statistical software for statistical analysis.themeasurement data with mean±standard deviation (x s),count data indicated aspercentage(%)，the comparison of rate and number of cases compared with the chi-square.Results:1. Constituent ratio:2466cases of inpatients with type2diabetes mellitus, in theminimum age was25years old，maximum age is90years old，the average age51.51±10.71. among which1568cases of male accounted for63.59%，female898accounting for36.42%. type2diabetes mellitus combined with hypertension（DH） patients,male608cases, accounting for58.13%, female438cases, accounting for41.87%,under the age of55,after the age of75, the proportion male of DH was higher than thefemale, However, in greater than or equal to55,less than75-year-old more women thanmen, the female proportion was higher than the male at the age of55～75group. the menproportion was at its peak in45～55year old age group, that of women peaked in55～65year old age group.2. The prevalence of DH:2466cases of T2DM patients,1046(42.42%) cases accordwith the diagnostic criteria of DH. the prevalence of DH female higher than male(48.775%vs38.776%), as the growth of the age, the prevalence of hypertension in men andwomen with diabetes have a rising trend，diabetic inpatients in hypertension prevalence,35to45years old, in the55to65years old, women higher than men (P <0.05).3. Regardless of inpatients diabetic patients grouped by blood pressure or groupedgender，the average age of DH group were significantly older than the DNP group.4. DH patients with different body mass index, sex ratio significantly different,overweight, under18Kg/m2(thin) two groups of male is significantly higher than femaleof which most overweight.18to24Kg/m2, obesity, two groups of women is higher thanmen, most proportion of which were18to24Kg/m2.5. As BMI increased, the prevalence of hypertension in diabetic patients with anupward trend, there was found statistical no differences, under28Kg/m2.male DHprevalence rate: normal weight, thin, overweight, obesity, there are differences among thefour groups, of which the lowest rate of normal weight prevalence.thin overweight, obesity,there are no differences among the three groups.different BMI of women DH prevalencehave difference. female prevalence of DH pairwise comparison was：four groups fromlargest to smallest order for obesity, normal weight overweight, thin.gender comparison: inthin, overweight two groups, the prevalence of DH in men higher than women.in obesity,normal weight two groups, the prevalence of DH in women higher than men.6. No matter what men or women, the average BMI of the DH patients were higherthan the DNP the average BMI of male were significantly higher than female in DHgroup.7. DH group, family history of hypertension, the proportion was significantly higher than DNP group (12.72%vs4.30%，X2=58.906、P＜0.005），the diabetic family historyproportion of the DH and DNP group was found no significant differences.in male, DNPand DH group the diabetic family history proportion was found no significant differences.the diabetic family proportion of female DNP group were significantly higher than that DHgroup（X2=5.039，P＜0.025）.no matter what men or women, the hypertensive familyproportion of DH patients was higher than DNP.no matter what men or women, thediabetic and hypertensive family proportion of DH patients was higher than the DNP. theproportion of DH patients was found no significant differences with diabetes mellituscomplicated hypertension，diabetes or hypertension family history between women groupand men group.the heredity of father or mother was found no significant differences inDNP and DH with diabetes or hypertension family history respectively. regardless ofinpatients diabetic patients grouped by blood pressure or grouped gender，mother weresignificantly higher than father with diabetes or hypertension family history respectively.8. Regardless of inpatients diabetic patients grouped by blood pressure or groupedgender, the allergic history proportion of the groups was found no significant differences.9. No matter which DH grading or layering, the proportion of men and women wasfound no significant differences. First grade hypertension was36.62％, second grade was42.64％,and third grade was20.75％, in DH patients. the proportion of high risk and veryhigh risk DH patients were36.71％and63.29%respectively.10.The complication rates of lipid abnormality, diabetic retinopathy diabeticnephropathy Ⅳ hyperuricemia Cerebral infarction and Coronary heart disease indiabeteswith hypertention were50.29%,48.95%,27.15%,17.59%,15.30%and28.87%respectively.these data were much higher than blood pressure groups. the incidence ofPeripheral neuropathy, diabetic nephropathyⅢ,Ⅴand heart failure was found nosignificant differences between the two groups.11.By different types from deficiency and excess，deficiency and excess interlace takean important part in Traditional Chinese Medicine of DH, which mainly displayed asQi-yin deficiency complicated with blood stasis type and phlegm complicated with bloodstasis of Qi deficiency type.at the first place was Qi-yin deficiency type, at the secondplace was liver kidney-yin deficiency type in deficiency Syndromes.the main excess syndromes type were blood stasis type and phlegm complicated with blood stasis type.12. Blood stasis and phlegmatic hygrosis was common and significant syndrome ofincorporation.at the first place was blood stasis, at the second place was phlegmatichygrosis.Conclusion:1. there were statistical differences. As the growth of the age, no matter whatmen or women, the prevalence of DH increased.2. The female average age of inpatient was significantly older than male.the averageage of DH were significantly older than DPN.3. As BMI increased, the prevalence of hypertension in diabetic patients with anupward trend, there was found statistical no differences, under28Kg/m2.4. The normal weight men rate of DH was lowest.there were no statistical differencesamong overweighted, emaciation and fatty. female prevalence of DH pairwise comparisonwas：four groups from largest to smallest order for obesity, normal weight, overweight,thin.5. No matter what men or women, the average BMI of the DH patients were higherthan the DNP.the average BMI of male were significantly higher than female in DH group.6. Positive family history of hypertension was the risk factors for DH.in diabetespatients there was maternally inherited factors.7. The allergic factor had no effect on hypertension in2diabetes mellitus patients.8. In diabetes combined with hypertension, in hypertension grade2, grade1, extremelyhigh risk, high risk, were given priority to.9. DH played an important role in accelerating occurrence and development ofkidney，retinopathy，brain and heart blood vessels complication，which had an importanteffect on hyperuricemia or lipid abnormality each other.10.By different types from deficiency and excess，deficiency and excess interlace takean important part in Traditional Chinese Medicine of DH, which mainly displayed asQi-yin deficiency complicated with blood stasis type and phlegm complicated with bloodstasis of Qi deficiency type.at the first place was Qi-yin deficiency type, at the secondplace was liver kidney-yin deficiency type in deficiency Syndromes.the main excesssyndromes type were blood stasis type and phlegm complicated with blood stasis type. 11. Blood stasis and phlegmatic hygrosis was common and significant syndrome ofincorporation.at the first place was blood stasis, at the second place was phlegmatichygrosis.