Coronary Heart Disease (CHD) In Patients With Carotid Atherosclerosis And The Correlation Of Syndrome Types Of TCM Research

Objective:Study to the coronary heart disease (coronary heart diseases, CHD) in patients with carotid atherosclerosis and the correlation of syndrome types of TCM. Methods: Choose between January2011and January2012in xinjiang medical university affiliated hospital of traditional Chinese medicine by coronary angiography diagnosis of625cases of elderly patients with coronary heart disease, according to the type can be divided into dirty phlegm syndrome, phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis, qi and Yin deficiency syndrome and other syndrome types, then the card type random dirty phlegm syndrome, phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis, qi and Yin deficiency syndrome,other syndromes distribution of syndromes. With192patients selected conditions of Chinese dirty phlegm syndrome syndrome, phlegm and blood stasis mutual resistance syndrome, Qi deficiency blood stasis, deficiency qi and Yin deficiency, as the association of carotid artery ultrasound and TCM syndrome type as the object of study, residual dirty phlegm obstruction syndrome78cases, phlegm stasis transresistance40cases,38cases of qi deficiency blood stasis syndrome, qi and Yin deficiency syndrome of36cases.Record all the object of study general information as well as traditional risk factors for coronary heart disease:include age, gender, race, hypertension, dyslipidemia, diabetes, smoking, obesity, and a positive family history, etc., detection of carotid ultrasound at the same time, to record the location of carotid ultrasonic IMT, plaque, the plaque integral, check the neck vascular stenosis degree integral and coronary artery lesion counts. Results:1) We select to625cases of diagnosis for patients with coronary heart disease (CHD), the distribution of TCM syndrome types for dirty phlegm obstruction syndrome (42.1%), phlegm and blood stasis resistance each accounted for25.2%, the proportion is bigger;2) comparing the coronary heart disease (CHD) various TCM syndrome types and neck vascular disease in single and double side, dirty phlegm obstruction syndrome incidence of cervical vascular unilateral43.6%, double side is56.4%; Phlegm stasis transresistance unilateral rate is30.0%, double side is70.0%;44.4%incidence of both qi and Yin deficiency syndrome after unilateral, bilateral is55.6%; Qi deficiency blood stasis unilateral incidence was50.0%, and50.0%on both sides, TCM syndrome type with single and double side neck position of correlation analysis, there was no statistically significant difference (P>0.05);3) Dirty phlegm syndrome, phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis, respectively, compared with qi and Yin deficiency syndrome, observation of78cases of dirty phlegm turbidity syndrome plaques found in64, which involved carotid, internal carotid artery and carotid artery bifurcation of8,12,44respectively, observing transresistance phlegm and blood stasis syndrome found in plaque32, which involving the common carotid, internal carotid artery and carotid artery bifurcation of6,2,24respectively, both groups with the most common carotid artery bifurcation, respectively accounted for68.8%,75.0%,29observation38patients with qi deficiency blood stasis that plaques, which involving the common carotid, internal carotid artery and carotid artery bifurcation10,3,16respectively, and the observation of36cases of qi deficiency blood stasis that plaque at24, which involving the common carotid, internal carotid artery and carotid artery bifurcation of7,7,10respectively.The syndrome types of traditional Chinese medicine patch position distribution no statistical difference;4) By comparing the different TCM syndrome type coronary heart disease and carotid ultrasound intima-media thickness (ima-media thickness, IMT), the results:dirty phlegm syndrome, phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis of IMT compared with qi and Yin deficiency syndrome, statistically significant difference (P<0.01, P<0.05); One dirty transresistance phlegm syndrome and phlegm stasis syndrome, qi deficiency blood stasis comparative differences are statistically significant differences (P<0.01); The comparison of carotid artery plaque integral, dirty phlegm obstruction syndrome, qi deficiency blood stasis and qi and Yin deficiency syndrome was statistically difference (P<0.01); Narrow degree integral comparison, dirty phlegm syndrome, phlegm stasis mutual resistance with qi and Yin deficiency syndrome was statistically difference (P<0.05);5) Coronary lesions and the occurrence of carotid artery sclerosis frequency, carotid plaques frequency correlation analysis, the difference was statistically significant (P<0.01);6) The coronary artery disease compare various TCM syndrome types lipid levels:dirty phlegm syndrome, phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis triglyceride levels compared with qi and Yin deficiency syndrome:use phlegm syndrome, phlegm and blood stasis mutual resistance syndrome, qi deficiency blood stasis triglyceride levels were significantly higher than those in the qi and Yin deficiency syndrome, the difference was statistically significant (P<0.01, P<0.05); Compare total cholesterol levels:dirty phlegm syndrome, phlegm stasis transresistance total cholesterol levels higher than that of qi and Yin deficiency, the difference was statistically significant (P<0.05); Phlegm stasis transresistance HDL lower than qi and Yin deficiency syndrome, the difference was statistically significant (P <0.05); Dirty phlegm syndrome, phlegm stasis transresistance LDL levels higher than that of qi and Yin deficiency syndrome, the difference was statistically significant (P<0.01, P<0.05). Conclusion:Degree of carotid atherosclerosis and the correlation between TCM syndrome types in patients with coronary heart disease, carotid ultrasound results can be used as objective basis indexes of coronary heart disease of traditional Chinese medicine, which will provide a scientific basis for clinical diagnosis and treatment of coronary heart disease.