The Study On The Correlation Between Hyperhidrosis And Atopy In Children

BackgroundIn our clinic, we have observed that more and more parents of children complain of excessive sweating accompanied by recurrent respiratory tract infection. Meanwhile, patients with allergic diseases are usually frustrated by hyperhidrosis (HH). Therefore, the relationship between HH and atopy should draw clinical attention. However, both at home and abroad, the studies on association between the two diseases mostly focus on adults. The researches carried out among children are scarce. Thus, we mean to explore the correlation between HH and atopy in children, which may provide new guidance for the treatment of pediatric HH and have important significance on preventing recurrent respiratory tract infection.ObjectiveTo explore the correlation between hyperhidrosis(HH) and atopy in children.Methods90children, who visited the pediatric clinic of the Fifth People’s Hospital of Shanghai Affiliated to Fudan University from August2010to March2012, were enrolled. According to the clinical manifestation, they were divided into two groups, the group of HH and the group of non-HH. Each group consisted of45children. The correlation between HH and allergic diseases such as infantile eczema (IEC) allergic rhinitis (AR), allergic conjunctivitis (AC) and asthma were analyzed by comparing the clinical characteristics between the two groups.Results1. The HH group and the non-HH group had no difference in gender, age, height, weight, BMI and other baseline data such as the absolute number of WBC, the percentage of eosinophil, calcium, phosphorus, alkaline phosphatase, and IgE in blood.2. HH and non-HH children had no difference in the family history of allergy (p>0.05). There were significant differences in the family history of excessive sweating between the two groups (p<0.05)3. There was no significant difference in the distribution of IEC, AR and AC between the HH group and the non-HH group (p>0.05). The morbidity of asthma in the HH group was higher than the non-HH group (p<0.05). And the allergy positive rate was also higher in the HH group.Conclusion1. Pediatric hyperhidrosis usually affects the head, neck and trunk.2. The children with excessive sweating usually have a positive family history of HH.3. Asthma and positive skin prick test are risk factors of HH in children, which indicate that HH may be associated with atopy. BackgroundAsthma is one of the most common chronic disorders of the airways in childhood. With the generalization and implement of the Global Strategy for Asthma Management and Prevention, the diagnosis and treatment of asthma has been unified and standardized. Moreover, the level of asthmatic diagnosis and treatment has been improved significantly. However, the morbidity of asthma, especially in childhood, is continuously rising. In our clinic, we have observed that not a few parents of asthmatic children complain of excessive sweating, which induces recurrent respiratory tract infection and asthmatic attack impairing the children’s health. However, both at home and abroad, documents studying the association between asthma and excessive sweating are scarce, most of which focus on adults. Therefore, we mean to explore the status of excessive sweating of asthmatic children while keeping quiet and associated risk factors, which may help to strengthen the diagnosis and treatment of asthma in childhood.ObjectiveTo investigate the prevalence of excessive sweating and determine the risk factors of excessive sweating in asthmatic children.Methods55children with confirmed asthma were recruited from the department of pediatrics of the Fifth People’s Hospital of Shanghai affiliated to Fudan University from August2010to March2012. According to the clinical manifestation, they were divided into two groups, the group of HH (n=34) and the group of non-HH (n=20). The correlation between HH and IEC, AR, AC were analyzed by comparing clinical characteristics between the two groups through the SPSS16.0package program (SPSS, Inc, Chicago, IL, USA)Results1. The HH group and the non-HH group had no difference in gender, age, height, weight, BMI and other baseline data such as calcium, phosphorus, alkaline phosphatase, IgE and the percentage of eosinophil in blood.2. There was no significant difference in the family history of HH and allergy between the two groups (p>0.05)3. There was no significant difference in the distribution of IEC and AC between the two groups (p>0.05). The morbidity of AR in the HH group was higher (p<0.05). And no significant difference was found in the positive rate of SPT between groups.Conclusion1. The prevalence of excessive sweating in asthmatic children is about63%.2. AR is the risk factors of excessive sweating in asthmatic children.