Metataitic Breast Caner TCM Syndrome Type And Western Medicine Molecular Points Of The Type Correlation

Objective:Through the preliminary discussion patients with metastatic breast cancer TCM syndrome type (the actual dialectical) and molecular parting correlation, through the initial analysis of the patients with metastatic breast cancer TCM syndrome type (the actual dialectical), western medicine and the relationship between the molecular subtypes prognosis for metastatic breast cancer combined with clinical diagnosis and treatment of Chinese and western provide preliminary reference.Methods:.118patients with metastatic breast cancer by deficiency syndrome, empirical, the actual mingled with card into three groups, deficiency syndrome group luminal type A, luminal type B, HER2+type, three negative type for16cases), respectively in5patients,6cases),3cases, empirical group luminal type A, luminal type B, HER2+type, three negative type number17cases, respectively in5cases,7cases,3cases, with the actual card group luminal type A, luminal type B, HER2+type, three negative type number for22cases respectively,6patients,5cases,23cases; And at the same time, to118cases of metastatic breast cancer by western medicine molecular parting points luminal type A, luminal type B, HER2+type, type of three negative four subtypes, luminal type A deficiency syndrome, in the inclusion, the actual card respectively for16cases),17cases,22cases, luminal type B deficiency syndrome, in the inclusion, the actual card in5cases, respectively in5patients,6cases, HER2+deficiency syndrome, empirical model, the actual card for6patients with respectively,7cases,5cases, three negative deficiency syndrome, empirical model, the actual card for3cases were mixed,3cases,23cases. Choose spss16.0software analysis two-way disorder R*C table material independence inspection; Statistical analysis of disease progression of time without the median. Three kinds of TCM syndrome type analysis in four different molecular subtypes constitute, at the same time, four kinds of different molecular analysis of3kinds of subtype TCM syndrome type composition. Preliminary statistics analysis of118cases of metastatic breast cancer three kinds of TCM syndrome type and the four categories of molecular subtypes of disease progression a no time.Results:1. Compared118cases of metastatic breast cancer three groups of TCM syndrome type4kinds of different molecular subtypes constitute a difference, showed three groups of TCM syndrome type4kinds of different molecular subtypes constitute a significant difference (a=0.05, P=0.008<0.05). The actual card patients with molecular points with empirical, virtual type constitute empirical there was significant difference (P=0.01<0.05), the empirical and deficiency syndrome patients molecular parting constitute no difference obvious (P=0.998>0.05). Three negative type and luminal type A, luminal type B, HER2+model more between the TCM syndrome type constitute A significant differences, metastatic three negative with breast cancer in the actual type of traditional Chinese medicine dialectical most for the actual performance with card type.2. With the actual card with breast cancer in a short period of disease progression in no other TCM syndrome type of breast cancer, three negative type with breast cancer in a short period of disease progression in no other molecules subtype.3. Metastatic breast cancer with the actual card more than empirical, deficiency syndrome.Conclusions:.1. The metastatic breast cancer and the actual type three negative correlation with card, metastatic breast cancer three negative type of traditional Chinese medicine dialectical trend with the actual actual card type2. Metastatic breast cancer patients with the actual card without progression of disease period is empirical, deficiency syndrome short, tumor progression faster, metastatic breast cancer three negative type disease progression period without A luminal type A, luminal type B, HER2+type patients short, tumor progression faster.3. Metastatic breast cancer patients with the actual card more than empirical, deficiency syndrome, suggesting metastatic breast cancer clinical much performance is virtual reality and pathogenesis complex.