Maixue Kang Capsule In The Treatment Of The Secondary Amenorrhea(Blood Stasis Syndrome) Clinical Observation

Objective: to observe the maixue kang capsule for pulse92cases secondary amenorrhea (blood stasis syndrome) the efficacy and safety of and to evaluate its effect.Methods:the May2011to2011between September and November meet the conditions of the outpatient as selected patients. In the patients with the ratio of3:1random points into two groups, according to each patient clinic of order and drug Numbers dispensing medication. The treatment group choose maixue kang capsule treatment group choose guizhi poria cocos capsule treatment, period of treatment for8weeks. Clinical observation indicators are (1) safety index:(1) the general medical project (therapy before, after therapy); Gynaecology (therapy,28days before treatment, after treatment).(2) the blood sedimentation, c-reactive protein, and abdominal B to exceed, urine pregnancy tests. Before treatment once detection.(3), and routine blood and urine tests. Before and after treatment were detection1time.(4) the heart (ecg), liver (ALT, AST), kidney (BUN, Cr) examination. Before and after treatment were detection1time. The whole body reaction (at any time record).(2) the curative effect of observation: menstrual changes (cycle, the quantity, the color and the quality). Secondary efficacy index: associated symptoms and tongue, pulse of change. Symptom: menstrual conditions, the lower abdomen pain, dry skin, skin a wrong, dry mouth do not want to drink, tongue dark purple, tongue edge bruises or stasis point, pulse sink powerful astringent, every four weeks during treatment records a total of three times observed.Results:before treatment, the treatment group and control group between gender, age, height, weight, blood pressure, heart rate and general material, vital signs, physical examination, duration, main symptom scores of TCM syndrome, such indicators and symptoms and signs of comparative differences between total score was not statistically significant (P>0.05). When the group that both groups of patients more balanced baseline index, with good comparability. After treatment, disease control group28.57%efficient curative effect, the treatment group31.34%, two groups of comparisons difference was statistically significant (P>0.05). Syndromes efficacy71.43%efficient control group, the treatment group67.16%, two groups of comparisons difference was statistically significant (P>0.05). TCM symptoms single curative effect analysis, after treatment with before treatment compared with statistical significance (P<0.05), but the difference between groups was statistically significant (P>0.05). This study observation period, two participants were vital signs are stable, no adverse events. In routine blood, then the normal, liver and kidney function, electrocardiogram several indicators appear in part the normal and the medicine before drug abnormal, the judge no clinical significance, or have clinical significance, but no significant correlation with drugs.Conclusion: maixue kang capsule in Cornwall, alleviate secondary amenorrhea (blood stasis syndrome) of menstruation for suspending, the lower abdomen pain, dry skin, skin symptoms such as a wrong have certain effect. In the clinical observation period did not find significant side effects, prompting the security is better. That maixue kang capsule in the treatment of secondary amenorrhea (blood stasis syndrome) have certain curative effect, taking safety.